Escherichia coli strain VREC0406

Escherichia coli strain VREC0406 is a Gram-negative, rod-shaped bacterium that exhibits motility, facilitated by the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the typical human body temperature. VREC0406 is host-associated and demonstrates a free-living biotic relationship across a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, various mammals, and even plants such as Solanum lycopersicum and Brassica oleracea var. italica. This extensive host range underscores its ecological versatility and potential for interaction with multiple species. The strain is associated with a variety of health effects, primarily in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Additionally, it has been implicated in foodborne infections and complications such as septicemia and renal failure. The presence of only one replicon and two membranes signifies its classification within the Enterobacteriaceae family. These traits, combined with its pathogenicity, underscore the importance of E. coli strain VREC0406 in both clinical and ecological contexts. Its ability to inhabit diverse environments and host species reflects its adaptability and potential impact on public health, particularly in relation to food safety and disease transmission.