Escherichia coli strain VREC0376

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VREC0376 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C, and typically exists in pairs or singles. VREC0376 is host-associated, demonstrating a free-living biotic relationship and exhibiting a wide host range that includes Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as numerous other vertebrates and invertebrates. The health impacts associated with E. coli strain VREC0376 are significant. It is known to cause a variety of infections, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and neonatal meningitis. The strain is linked to a range of health issues from foodborne infections and enteric diseases to complications like hemolytic uremic syndrome (HUS) and renal failure. The diverse array of hosts and the range of health effects underscore the ecological versatility and pathogenic potential of E. coli strain VREC0376. This adaptability highlights the importance of monitoring such strains in both clinical and environmental contexts, as their presence can have serious implications for public health, particularly in relation to zoonotic transmission and food safety. Understanding the interactions of this strain with its hosts can aid in developing strategies to mitigate its pathogenic effects and improve health outcomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VREC0376

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VREC0376
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VREC0376 genome assembly, contig:

Gene Summary

Adenine Count

1354521 bp

Thymine Count

1357943 bp

Guanine Count

1361318 bp

Cytosine Count

1368393 bp

Genome Length

5442589 bp

Protein-coding Genes

4834 genes

Non-Coding Genes

462 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3472044_05024Not AvailableNegative4982199 - 49823064137.41
abortive infection bacteriophage resistance proteinSAMEA3472044_05025Not AvailableNegative4982341 - 498329737347.5
uncharacterised proteinSAMEA3472044_05026Not AvailableNegative4983797 - 49840369013.8
uncharacterised proteinSAMEA3472044_05027Not AvailablePositive4984131 - 498492230359.7
uncharacterised proteinSAMEA3472044_05028Not AvailablePositive4985077 - 49853349606.53
uncharacterised proteinSAMEA3472044_05029Not AvailableNegative4985430 - 498587616142.7
is5 transposase and trans-activatorSAMEA3472044_05030Not AvailablePositive4986179 - 498690427683.2
insertion sequence is100, atp-binding proteinSAMEA3472044_05031Not AvailableNegative4986914 - 498769329284.5
transposase orf a, is100 (fragment)SAMEA3472044_05032Not AvailableNegative4987693 - 49878214815.75
is5 transposase and trans-activatorSAMEA3472044_05033Not AvailablePositive4988384 - 498872813605.6

Displaying genes 4921 – 4930 of 5296 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total