Staphylococcus aureus strain NCTC7878

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus strain NCTC7878 is a Gram-positive cocci bacterium that typically exhibits a cluster arrangement, appearing as singles or in groups. It is a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic conditions. This strain is non-motile and does not possess flagella. Its temperature range is mesophilic, with an optimal growth temperature of 3°C, and it contains a single membrane and a single replicon. NCTC7878 is associated with a wide variety of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus), cows (Bos taurus), and various other mammals. This broad host range signifies its adaptability and potential for transmission across species. The strain is known to cause numerous health issues such as vertebral osteomyelitis, bacteremia, pneumonia, and skin and soft tissue infections, among others. Its pathogenicity affects both humans and animals, indicating its role as an opportunistic pathogen. The ecological insight provided by this strain is its ability to exist in a free-living state while still being associated with diverse hosts. This dual lifestyle may facilitate its transmission and persistence in various environments, raising concerns for public health and animal health alike. Given its association with a significant number of infections and its potential role in food safety incidents, understanding S. aureus NCTC7878 is crucial for developing strategies to mitigate its impact on health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
Strainstrain NCTC7878

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus strain NCTC7878
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature3
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genome Summary

Staphylococcus aureus strain NCTC7878 genome assembly, contig:

Gene Summary

Adenine Count

934137 bp

Thymine Count

939351 bp

Guanine Count

461345 bp

Cytosine Count

455714 bp

Genome Length

2790547 bp

Protein-coding Genes

3408 genes

Non-Coding Genes

244 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
oxai/yidc membrane insertion proteinNCTC7878_02840Not AvailableNegative2129040 - 212991233583.1
thiamin-phosphate pyrophosphorylaseNCTC7878_02841Not AvailableNegative2130005 - 213064023166.5
hydroxyethylthiazole kinaseNCTC7878_02842Not AvailableNegative2130754 - 213143423779.7
phosphomethylpyrimidine kinaseNCTC7878_02843Not AvailableNegative2131418 - 213224830213.3
transcriptional activator tenaNCTC7878_02844Not AvailableNegative2132241 - 213293026842.1
protein of uncharacterised function (duf3125)NCTC7878_02846Not AvailablePositive2133193 - 213346511036.5
sced-like transglycosylase, biomarker for vancomycin-intermediate strainsNCTC7878_02847Not AvailableNegative2133455 - 213387714419.2
sced-like transglycosylase, biomarker for vancomycin-intermediate strainsNCTC7878_02848Not AvailableNegative2133990 - 21341515411.38
single-stranded dna-binding proteinNCTC7878_02849Not AvailableNegative2134541 - 213493615071.0
uncharacterised proteinNCTC7878_02850Not AvailablePositive2135132 - 213557217136.5

Displaying genes 2841 – 2850 of 3652 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionsCausesPMC10127087
Bones and joint infectionsCausesPMC10127087
Infective endocarditisCausesPMC10127087
Cardiovascular disordersCausesPMC10127087
OsteomyelitisCausesPMC10127087
BacteremiaCausesPMC10127087
PneumoniaCausesPMC10127087
Skin and soft tissue infectionsCausesPMC10269700
EndocarditisCausesPMC10269700
PneumoniaCausesPMC10269700

Displaying health effects 1 – 10 of 115 in total