Staphylococcus aureus strain NCTC7878

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus strain NCTC7878 is a Gram-positive cocci bacterium that typically exhibits a cluster arrangement, appearing as singles or in groups. It is a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic conditions. This strain is non-motile and does not possess flagella. Its temperature range is mesophilic, with an optimal growth temperature of 3°C, and it contains a single membrane and a single replicon. NCTC7878 is associated with a wide variety of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus), cows (Bos taurus), and various other mammals. This broad host range signifies its adaptability and potential for transmission across species. The strain is known to cause numerous health issues such as vertebral osteomyelitis, bacteremia, pneumonia, and skin and soft tissue infections, among others. Its pathogenicity affects both humans and animals, indicating its role as an opportunistic pathogen. The ecological insight provided by this strain is its ability to exist in a free-living state while still being associated with diverse hosts. This dual lifestyle may facilitate its transmission and persistence in various environments, raising concerns for public health and animal health alike. Given its association with a significant number of infections and its potential role in food safety incidents, understanding S. aureus NCTC7878 is crucial for developing strategies to mitigate its impact on health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
Strainstrain NCTC7878

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus strain NCTC7878
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature3
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genome Summary

Staphylococcus aureus strain NCTC7878 genome assembly, contig:

Gene Summary

Adenine Count

934137 bp

Thymine Count

939351 bp

Guanine Count

461345 bp

Cytosine Count

455714 bp

Genome Length

2790547 bp

Protein-coding Genes

3408 genes

Non-Coding Genes

244 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hydrolaseNCTC7878_01673Not AvailableNegative1248354 - 124892321794.1
femb, factor involved in methicillin resistance / glycine interpeptide bridge formationNCTC7878_01674Not AvailableNegative1249786 - 125053229694.1
femb, factor involved in methicillin resistance / glycine interpeptide bridge formationNCTC7878_01675Not AvailableNegative1250560 - 125104518982.5
udp-n-acetylmuramoylpentapeptide-glycine glycyltransferaseNCTC7878_01676Not AvailableNegative1251042 - 125170425760.4
udp-n-acetylmuramoylpentapeptide-glycine glycyltransferaseNCTC7878_01677Not AvailableNegative1251766 - 125232321664.8
tryptophan synthase subunit alphaNCTC7878_01678Not AvailableNegative1252653 - 12528145929.19
tryptophan synthase subunit alphaNCTC7878_01679Not AvailableNegative1252939 - 125337016158.6
tryptophan synthase beta chainNCTC7878_01680Not AvailableNegative1253363 - 125371012668.9
tryptophan synthase beta chainNCTC7878_01681Not AvailableNegative1253701 - 125457632095.9
phosphoribosylanthranilate isomeraseNCTC7878_01682Not AvailableNegative1254831 - 125520213737.8

Displaying genes 1811 – 1820 of 3652 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionsCausesPMC10127087
Bones and joint infectionsCausesPMC10127087
Infective endocarditisCausesPMC10127087
Cardiovascular disordersCausesPMC10127087
OsteomyelitisCausesPMC10127087
BacteremiaCausesPMC10127087
PneumoniaCausesPMC10127087
Skin and soft tissue infectionsCausesPMC10269700
EndocarditisCausesPMC10269700
PneumoniaCausesPMC10269700

Displaying health effects 1 – 10 of 115 in total