Mycobacterium xenopi strain NCTC10042

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium xenopi strain NCTC10042 is a notable mycobacterial species primarily found in drinking water. This organism is characterized by the presence of flagella, which may play a role in its motility within aquatic environments. M. xenopi has a single replicon, indicating a streamlined genetic organization. This strain has been identified as a pathogen in various hosts, including Homo sapiens, Metazoa, and Felis catus. In humans, it is associated with several health conditions, particularly pulmonary disease and non-tuberculous mycobacterial pulmonary disease (NTM-PD). Additional health effects include disseminated disease and localized lesions, highlighting its potential to cause serious infections beyond the respiratory system. The presence of M. xenopi in drinking water suggests that this environment can serve as a reservoir for potential infections, particularly in immunocompromised individuals or those with preexisting lung conditions. This aspect underscores the importance of monitoring and managing water quality to mitigate the risk of exposure to pathogenic mycobacteria. Understanding the ecological distribution and health implications of M. xenopi can inform public health strategies and contribute to the prevention of mycobacterial diseases. The genetic information associated with this strain is cataloged under the accession number UATA00000000.1, providing a resource for further research into its characteristics and effects on health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium xenopi
Strainstrain NCTC10042

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatDrinking water
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Felis catus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium xenopi strain NCTC10042 genome assembly, contig:

Gene Summary

Adenine Count

899992 bp

Thymine Count

891151 bp

Guanine Count

1721959 bp

Cytosine Count

1738834 bp

Genome Length

5251936 bp

Protein-coding Genes

4996 genes

Non-Coding Genes

125 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosomal large subunit pseudouridine synthase bNCTC10042_04613Not AvailableNegative4699603 - 470034026397.2
transcriptional regulatorNCTC10042_04614Not AvailableNegative4700340 - 470103524982.6
segregation and condensation protein aNCTC10042_04615Not AvailableNegative4701085 - 470191830573.6
putative initiation inhibitor proteinNCTC10042_04616Not AvailableNegative4701915 - 470277831167.6
o-methyltransferaseNCTC10042_04617Not AvailablePositive4703122 - 470387427381.6
site-specific tyrosine recombinase xerdNCTC10042_04618Not AvailableNegative4703893 - 470484033918.7
mutt/nudix family proteinNCTC10042_04619Not AvailableNegative4704837 - 470546022766.1
ctp synthaseNCTC10042_04620Not AvailableNegative4705453 - 470721063933.2
outer membrane proteinNCTC10042_04621Not AvailableNegative4707341 - 470828531787.7
thiamin pyrophosphokinaseNCTC10042_04622Not AvailableNegative4708298 - 470947341830.4

Displaying genes 4591 – 4600 of 5121 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ntm-pdCausesPMC11100324
Mycobacterial diseasesCausesPMC5276850
Pulmonary diseaseCausesPMC5759224
Disseminated diseaseCausesPMC5759224
Localized lesionsCausesPMC5759224

Displaying health effects 1 – 5 of 5 in total