Mycobacterium xenopi strain NCTC10042

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium xenopi strain NCTC10042 is a notable mycobacterial species primarily found in drinking water. This organism is characterized by the presence of flagella, which may play a role in its motility within aquatic environments. M. xenopi has a single replicon, indicating a streamlined genetic organization. This strain has been identified as a pathogen in various hosts, including Homo sapiens, Metazoa, and Felis catus. In humans, it is associated with several health conditions, particularly pulmonary disease and non-tuberculous mycobacterial pulmonary disease (NTM-PD). Additional health effects include disseminated disease and localized lesions, highlighting its potential to cause serious infections beyond the respiratory system. The presence of M. xenopi in drinking water suggests that this environment can serve as a reservoir for potential infections, particularly in immunocompromised individuals or those with preexisting lung conditions. This aspect underscores the importance of monitoring and managing water quality to mitigate the risk of exposure to pathogenic mycobacteria. Understanding the ecological distribution and health implications of M. xenopi can inform public health strategies and contribute to the prevention of mycobacterial diseases. The genetic information associated with this strain is cataloged under the accession number UATA00000000.1, providing a resource for further research into its characteristics and effects on health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium xenopi
Strainstrain NCTC10042

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatDrinking water
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Felis catus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium xenopi strain NCTC10042 genome assembly, contig:

Gene Summary

Adenine Count

899992 bp

Thymine Count

891151 bp

Guanine Count

1721959 bp

Cytosine Count

1738834 bp

Genome Length

5251936 bp

Protein-coding Genes

4996 genes

Non-Coding Genes

125 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inositol-phosphate phosphatase impaNCTC10042_02129Not AvailableNegative2192284 - 219308427831.1
phosphoribosyl isomerase aNCTC10042_02130Not AvailableNegative2193087 - 219382425609.4
amidotransferaseNCTC10042_02131Not AvailableNegative2193821 - 219444121633.1
imidazoleglycerol-phosphate dehydrataseNCTC10042_02132Not AvailableNegative2194438 - 219505222334.5
histidinol-phosphate amino transferaseNCTC10042_02133Not AvailableNegative2195049 - 219617339842.5
histidinol dehydrogenaseNCTC10042_02134Not AvailableNegative2196170 - 219750145597.2
deazaflavin-dependent nitroreductase family proteinNCTC10042_02135Not AvailablePositive2197589 - 219795713752.0
theronine dehydrogenase-like zn-dependent dehydrogenaseNCTC10042_02136Not AvailableNegative2197969 - 219899736248.5
transcriptional regulatorNCTC10042_02137Not AvailablePositive2199048 - 219965021454.7
nicotinate-nucleotide pyrophosphorylase (carboxylating)NCTC10042_02138Not AvailableNegative2199691 - 220055430082.0

Displaying genes 2141 – 2150 of 5121 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ntm-pdCausesPMC11100324
Mycobacterial diseasesCausesPMC5276850
Pulmonary diseaseCausesPMC5759224
Disseminated diseaseCausesPMC5759224
Localized lesionsCausesPMC5759224

Displaying health effects 1 – 5 of 5 in total