Mycobacterium xenopi strain NCTC10042

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium xenopi strain NCTC10042 is a notable mycobacterial species primarily found in drinking water. This organism is characterized by the presence of flagella, which may play a role in its motility within aquatic environments. M. xenopi has a single replicon, indicating a streamlined genetic organization. This strain has been identified as a pathogen in various hosts, including Homo sapiens, Metazoa, and Felis catus. In humans, it is associated with several health conditions, particularly pulmonary disease and non-tuberculous mycobacterial pulmonary disease (NTM-PD). Additional health effects include disseminated disease and localized lesions, highlighting its potential to cause serious infections beyond the respiratory system. The presence of M. xenopi in drinking water suggests that this environment can serve as a reservoir for potential infections, particularly in immunocompromised individuals or those with preexisting lung conditions. This aspect underscores the importance of monitoring and managing water quality to mitigate the risk of exposure to pathogenic mycobacteria. Understanding the ecological distribution and health implications of M. xenopi can inform public health strategies and contribute to the prevention of mycobacterial diseases. The genetic information associated with this strain is cataloged under the accession number UATA00000000.1, providing a resource for further research into its characteristics and effects on health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium xenopi
Strainstrain NCTC10042

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatDrinking water
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Felis catus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium xenopi strain NCTC10042 genome assembly, contig:

Gene Summary

Adenine Count

899992 bp

Thymine Count

891151 bp

Guanine Count

1721959 bp

Cytosine Count

1738834 bp

Genome Length

5251936 bp

Protein-coding Genes

4996 genes

Non-Coding Genes

125 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
plp-dependent enzyme, histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylaseNCTC10042_00176Not AvailablePositive188773 - 18981636830.6
dinuclear metal center protein, ybgi/sa1388 familyNCTC10042_00177Not AvailablePositive189813 - 19095239827.0
zn-ribbon protein, possibly nucleic acid-binding proteinNCTC10042_00178Not AvailablePositive190949 - 19168627483.2
bifunctional rnase h/acid phosphataseNCTC10042_00179Not AvailablePositive191683 - 19279239840.1
n-acyl-d-aspartate/d-glutamate deacylaseNCTC10042_00181Not AvailableNegative194027 - 19574860604.7
putative tim-barrel fold metal-dependent hydrolaseNCTC10042_00182Not AvailableNegative195742 - 19693843932.9
conserved protein of uncharacterised function with pin domain, possible toxin vapc13NCTC10042_00183Not AvailableNegative197360 - 19775514722.8
conserved protein of uncharacterised function, possible antitoxin vapb13NCTC10042_00184Not AvailableNegative197764 - 1980159708.48
aldehyde dehydrogenaseNCTC10042_00185Not AvailableNegative198071 - 19955550761.6
zinc-dependent alcohol dehydrogenase adhe2NCTC10042_00186Not AvailablePositive199621 - 20075138182.9

Displaying genes 201 – 210 of 5121 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ntm-pdCausesPMC11100324
Mycobacterial diseasesCausesPMC5276850
Pulmonary diseaseCausesPMC5759224
Disseminated diseaseCausesPMC5759224
Localized lesionsCausesPMC5759224

Displaying health effects 1 – 5 of 5 in total