Morganella morganii strain NCTC12358

Morganella morganii strain NCTC12358 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape. This mesophilic organism is commonly found in natural environments, particularly in sewage. It has a single replicon and is known to infect a variety of hosts, including Homo sapiens and Acanthamoeba castellanii. This strain is associated with a range of health effects in humans, including intra-abdominal infections, wound infections, sepsis, urinary tract infections, and cellulitis. It also contributes to more severe conditions such as endophthalmitis, post-operative wound infections, and infectious ocular diseases. Notably, it has been linked to "purple urine bag syndrome," a condition often seen in patients with long-term urinary catheters, as well as summer diarrhea and hepatobiliary infections. The ecological role of Morganella morganii, particularly in sewage, highlights its potential as a pathogen in human health contexts, especially in settings where sanitation may be compromised. Its ability to thrive in both anaerobic and aerobic environments allows it to adapt to various ecological niches, reinforcing its significance as a pathogen in both community and healthcare-associated infections. Understanding the habitats and conditions that favor this bacterium can aid in developing strategies for infection prevention and control, particularly in vulnerable populations.