Escherichia coli strain NCTC9073

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9073 is a Gram-negative, rod-shaped bacterium that exists predominantly in pairs and singles. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic range. This strain possesses flagella, enabling mobility, and has a biotic relationship characterized as free-living. NCTC9073 is associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates. Its wide host range indicates a versatile ecological role, allowing it to exploit diverse environments. This strain is notably pathogenic to humans, linked to numerous health issues, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS). It has been implicated in peritonitis, neonatal meningitis, and foodborne infections, showcasing its potential as a significant clinical pathogen. Given its capacity to cause a variety of diseases, including diarrheal diseases and central nervous system infections, NCTC9073 serves as a critical example of how a single microbial strain can impact both human health and veterinary medicine. Its presence across multiple hosts highlights the interconnectedness of ecosystems and the potential for zoonotic transmission of pathogenic strains. Understanding its characteristics can aid in monitoring and controlling infections associated with this strain, emphasizing the importance of further research in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9073

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9073
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9073 genome assembly, contig:

Gene Summary

Adenine Count

1179449 bp

Thymine Count

1171475 bp

Guanine Count

1167825 bp

Cytosine Count

1242994 bp

Genome Length

4761743 bp

Protein-coding Genes

6197 genes

Non-Coding Genes

345 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glyoxylate carboligase (tartronate-semialdehyde synthase)NCTC9073_02845Not AvailableNegative2069112 - 20692254058.09
glyoxylate carboligase (tartronate-semialdehyde synthase)NCTC9073_02846Not AvailableNegative2069405 - 206972511076.5
negative regulator of allantoin and glyoxylate utilization operonsNCTC9073_02847Not AvailableNegative2069844 - 207065929271.4
ureidoglycolate hydrolaseNCTC9073_02848Not AvailableNegative2070737 - 207121918223.6
lysr family transcriptional regulatorNCTC9073_02849Not AvailablePositive2071449 - 207237534513.6
trna 2-selenouridine synthaseNCTC9073_02850Not AvailablePositive2072444 - 207353841157.2
dna-binding transcriptional regulatorNCTC9073_02851Not AvailablePositive2073654 - 207402513988.7
rhs-likeNCTC9073_02852Not AvailableNegative2075040 - 207571725783.5
proteinNCTC9073_02853Not AvailableNegative2075717 - 207608514153.2
rhsd proteinNCTC9073_02854Not AvailableNegative2076125 - 207726442899.6

Displaying genes 3001 – 3010 of 6542 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total