Escherichia coli strain NCTC11126

Escherichia coli strain NCTC11126 is a Gram-negative, rod-shaped bacterium that exhibits mobility through the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is primarily host-associated but can be found free-living in various habitats. Its optimal growth temperature is 37°C, aligning with its mesophilic nature. NCTC11126 has a single replicon and is characterized by having two membranes, typical of Gram-negative bacteria. It has a wide range of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as other vertebrates and invertebrates, demonstrating its ecological versatility. This strain is notably pathogenic to humans, being implicated in a variety of health effects, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Its ability to cause diverse infections underscores its significance in clinical microbiology and public health. The extensive range of hosts and pathogenic potential of E. coli NCTC11126 highlights its adaptability and the complexity of host-pathogen interactions within various biological systems. This adaptability is crucial in understanding its role in health and disease, particularly in the context of foodborne infections and antibiotic resistance. Understanding this strain's biology can aid in developing preventive measures and therapeutic strategies against its associated health risks.