Bacillus cereus strain NCTC6474

Gram-positiveRodMotileAerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Bacillaceae

Genus

Bacillus

Description

Bacillus cereus strain NCTC6474 is a Gram-positive, rod-shaped bacterium that exhibits a chain-like cell arrangement and is classified as an aerobe, requiring oxygen for growth. This strain is motile, possessing flagella, and thrives at an optimal temperature of 25°C within a mesophilic temperature range. It is free-living, with a single membrane and a single replicon. This bacterium is notable for its diverse biotic relationships, as it can inhabit multiple environments and has been associated with various hosts, including Homo sapiens, Gallus gallus, and several other Metazoa, Insecta, and Mammalia species. Its pathogenicity is particularly concerning in humans, where it has been linked to a wide array of health effects, including bacteremia, pneumonia, meningitis, and food poisoning. The strain is implicated in severe conditions such as necrotizing fasciitis, endocarditis, and systemic multi-organ failure, highlighting its potential to cause serious infections. Bacillus cereus can also lead to non-gastrointestinal infections and various syndromes associated with foodborne illnesses, such as the emetic and diarrheal syndromes. Its ability to affect both mammals and insects indicates a versatile ecological role, potentially influencing food safety and public health. This adaptability and pathogenicity underscore the importance of monitoring and controlling B. cereus in various environments to mitigate health risks associated with this bacterium.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyBacillaceae
GenusBacillus
SpeciesBacillus cereus
Strainstrain NCTC6474

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Bacillus cereus strain NCTC6474
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature25
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Bacillus cereus strain NCTC6474 genome assembly, contig:

Gene Summary

Adenine Count

1863709 bp

Thymine Count

1838709 bp

Guanine Count

1034937 bp

Cytosine Count

966696 bp

Genome Length

5704051 bp

Protein-coding Genes

5639 genes

Non-Coding Genes

212 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp:guanido phosphotransferaseNCTC6474_05813Not AvailablePositive5539589 - 554035328486.5
atp:guanido phosphotransferaseNCTC6474_05814Not AvailablePositive5540519 - 55406595413.71
negative regulator of genetic competence clpc/mecbNCTC6474_05815Not AvailablePositive5540672 - 55408004920.96
sodium/alanine symporter family proteinNCTC6474_05816Not AvailableNegative5541458 - 554290051435.6
uncharacterised proteinNCTC6474_05817Not AvailableNegative5542884 - 55430516743.66
sodium/alanine symporter family proteinNCTC6474_05818Not AvailableNegative5543236 - 554466651331.4
nadh-flavin reductaseNCTC6474_05819Not AvailablePositive5544967 - 554560522735.8
wall-associated proteinNCTC6474_05820Not AvailableNegative5545649 - 5550079167862.0
collagen adhesion proteinNCTC6474_05821Not AvailableNegative5550638 - 555156134476.2
oxidoreductase, aldo/keto reductase familyNCTC6474_05822Not AvailableNegative5551675 - 555251431813.8

Displaying genes 5691 – 5700 of 5851 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Late-onset neonatal sepsisCausesPMC11282708
Neonatal sepsisCausesPMC11282708
Food poisoningCausesPMC11282708
SepsisCausesPMC11282708
MeningitisCausesPMC11282708
PneumoniaCausesPMC11282708
Foodborne illnessesCausesPMC11282708
Severe systemic multi-organ failureCausesPMC11282708
Anthrax-like skin infectionsCausesPMC11282708
Severe neonatal skin infections resembling anthrax-like lesionsCausesPMC11282708

Displaying health effects 1 – 10 of 75 in total