Bacillus cereus strain NCTC6474

Gram-positiveRodMotileAerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Bacillaceae

Genus

Bacillus

Description

Bacillus cereus strain NCTC6474 is a Gram-positive, rod-shaped bacterium that exhibits a chain-like cell arrangement and is classified as an aerobe, requiring oxygen for growth. This strain is motile, possessing flagella, and thrives at an optimal temperature of 25°C within a mesophilic temperature range. It is free-living, with a single membrane and a single replicon. This bacterium is notable for its diverse biotic relationships, as it can inhabit multiple environments and has been associated with various hosts, including Homo sapiens, Gallus gallus, and several other Metazoa, Insecta, and Mammalia species. Its pathogenicity is particularly concerning in humans, where it has been linked to a wide array of health effects, including bacteremia, pneumonia, meningitis, and food poisoning. The strain is implicated in severe conditions such as necrotizing fasciitis, endocarditis, and systemic multi-organ failure, highlighting its potential to cause serious infections. Bacillus cereus can also lead to non-gastrointestinal infections and various syndromes associated with foodborne illnesses, such as the emetic and diarrheal syndromes. Its ability to affect both mammals and insects indicates a versatile ecological role, potentially influencing food safety and public health. This adaptability and pathogenicity underscore the importance of monitoring and controlling B. cereus in various environments to mitigate health risks associated with this bacterium.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyBacillaceae
GenusBacillus
SpeciesBacillus cereus
Strainstrain NCTC6474

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Bacillus cereus strain NCTC6474
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature25
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Bacillus cereus strain NCTC6474 genome assembly, contig:

Gene Summary

Adenine Count

1863709 bp

Thymine Count

1838709 bp

Guanine Count

1034937 bp

Cytosine Count

966696 bp

Genome Length

5704051 bp

Protein-coding Genes

5639 genes

Non-Coding Genes

212 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
carbamoyl phosphate synthase small subunitNCTC6474_01823Not AvailablePositive1769383 - 177050441249.3
carbamoyl phosphate synthase large subunitNCTC6474_01824Not AvailablePositive1770489 - 1773707118589.0
dihydroorotate dehydrogenase electron transfer subunitNCTC6474_01825Not AvailablePositive1773704 - 177448328404.5
dihydroorotate dehydrogenase 1bNCTC6474_01826Not AvailablePositive1774480 - 177540932978.0
orotidine 5'-phosphate decarboxylaseNCTC6474_01827Not AvailablePositive1775394 - 177611026180.7
phage integrase domain protein sam domain proteinNCTC6474_01828Not AvailableNegative1776716 - 17769649709.6
replication proteinNCTC6474_01829Not AvailableNegative1778035 - 177904539018.3
prophage helix-turn-helix proteinNCTC6474_01830Not AvailablePositive1779575 - 178069943829.0
uncharacterised proteinNCTC6474_01831Not AvailablePositive1780718 - 17808434389.53
uncharacterised proteinNCTC6474_01832Not AvailablePositive1780971 - 17811266105.42

Displaying genes 1921 – 1930 of 5851 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Late-onset neonatal sepsisCausesPMC11282708
Neonatal sepsisCausesPMC11282708
Food poisoningCausesPMC11282708
SepsisCausesPMC11282708
MeningitisCausesPMC11282708
PneumoniaCausesPMC11282708
Foodborne illnessesCausesPMC11282708
Severe systemic multi-organ failureCausesPMC11282708
Anthrax-like skin infectionsCausesPMC11282708
Severe neonatal skin infections resembling anthrax-like lesionsCausesPMC11282708

Displaying health effects 1 – 10 of 75 in total