Klebsiella pneumoniae strain ST15 115

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain ST15 115 is a Gram-negative, rod-shaped bacterium that exhibits a diverse range of pathogenic effects in humans and other hosts. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It typically forms chains, pairs, or single cells, and possesses flagella, contributing to its motility. As a chemoheterotroph, K. pneumoniae ST15 115 relies on organic compounds for energy, which it can derive from various host organisms, including Homo sapiens, Gallus gallus, and others across several taxa such as Metazoa and Viridiplantae. The strain is associated with numerous health complications, including bacteremia, urinary tract infections, pneumonia, meningitis, and sepsis, highlighting its significant role as a human pathogen. The optimal growth temperature for K. pneumoniae ST15 115 is 37°C, placing it within the mesophilic temperature range. It features a typical bacterial structure with two membranes and a single replicon, suggesting a streamlined genomic organization conducive to its adaptability in host-associated habitats. The presence of K. pneumoniae in various hosts illustrates its ecological versatility and potential for cross-species transmission. Its pathogenicity in humans underscores the importance of monitoring and controlling infections caused by this strain, particularly in clinical settings where vulnerable populations may be at risk. Understanding its ecological relationships can inform strategies aimed at mitigating its impact on human health and managing outbreaks effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain ST15 115

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain ST15 115
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain ST15 115, whole genome shotgun

Gene Summary

Adenine Count

1223819 bp

Thymine Count

1209056 bp

Guanine Count

1602794 bp

Cytosine Count

1626885 bp

Genome Length

5662554 bp

Protein-coding Genes

5193 genes

Non-Coding Genes

383 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phenylacetate-coa oxygenase subunit paajFCN83_17290Not AvailablePositive3601561 - 360205818356.0
phenylacetate-coa oxygenase/reductase subunit paakFCN83_17295Not AvailablePositive3602066 - 360313638993.6
2,3-dehydroadipyl-coa hydrataseFCN83_17300Not AvailablePositive3603133 - 360390027426.1
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-coa isomeraseFCN83_17305Not AvailablePositive3603903 - 360469128077.8
3-hydroxyacyl-coa dehydrogenase paacFCN83_17310Not AvailablePositive3604695 - 360611650776.2
hydroxyphenylacetyl-coa thioesterase paaiFCN83_17315Not AvailablePositive3606106 - 360652815177.2
3-oxoadipyl-coa thiolaseFCN83_17320Not AvailablePositive3606528 - 360773342143.8
phenylacetate--coa ligaseFCN83_17325Not AvailablePositive3607760 - 360907649027.9
phenylacetic acid degradation operon negative regulatory protein paaxFCN83_17330Not AvailablePositive3609187 - 361012234768.2
phenylacetic acid degradation protein paayFCN83_17335Not AvailablePositive3610132 - 361072821193.6

Displaying genes 3741 – 3750 of 5576 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total