Escherichia coli strain SIEC109 118_NODE_121

Escherichia coli strain SIEC109 (118_NODE_121) is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and capable of mobility due to the presence of flagella. This strain is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other vertebrates and invertebrates, indicating its broad ecological and biological versatility. With a mesophilic optimal growth temperature of 37°C, strain SIEC109 thrives in temperature ranges conducive to warm-blooded hosts. Its habitat is classified as host-associated, suggesting a close relationship with its hosts, where it can exhibit free-living behaviors as well. SIEC109 is linked to numerous health effects, particularly in humans, where it is known to cause urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like neonatal meningitis and hemolytic uremic syndrome (HUS). This pathogenicity underscores its significance in medical microbiology, as it can lead to a variety of diseases, including diarrhea, peritonitis, and even food poisoning. The strain's extensive list of health effects highlights its role as a significant opportunistic pathogen, particularly in vulnerable populations such as neonates and individuals with weakened immune systems. Given its diverse range of hosts and pathogenic potential, E. coli strain SIEC109 serves as a critical example of how microbial interactions can influence health outcomes across species. Understanding its ecological dynamics and pathogenic mechanisms can provide valuable insights into managing its associated health risks in both human and animal populations.