Escherichia coli strain SIEC025 26_NODE_81

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SIEC025 26_NODE_81 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. It is mesophilic, with an optimal growth temperature of 37°C. SIEC025 has a single replicon and is characterized by a double membrane structure. It is associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other species across multiple taxa such as Mammalia, Aves, and Mollusca. This strain is known for its pathogenicity in humans, contributing to a wide range of health issues. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and serious conditions such as septicemia and neonatal meningitis. Other health effects linked to SIEC025 include diarrheal diseases, colibacillosis, and complications like hemolytic uremic syndrome (HUS). The extensive list of hosts suggests that SIEC025 is a versatile bacterium capable of surviving in diverse ecological niches. Its ability to infect various species, including humans and livestock, highlights its role in zoonotic transmission and foodborne infections. The strain's association with both environmental and host-associated habitats underscores its adaptive capacity, which may have implications for public health and veterinary medicine, particularly in managing infections and preventing disease outbreaks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain SIEC025 26_NODE_81

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain SIEC025 26_NODE_81
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SIEC025 26_NODE_81, whole genome shotgun

Gene Summary

Adenine Count

1263169 bp

Thymine Count

1268945 bp

Guanine Count

1281459 bp

Cytosine Count

1290488 bp

Genome Length

5104061 bp

Protein-coding Genes

4496 genes

Non-Coding Genes

377 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tonb system transport protein tonbFCU53_23980Not AvailablePositive4942635 - 494335125921.4
acyl-coa thioester hydrolase yciaFCU53_23985Not AvailableNegative4943391 - 494378914231.4
septation protein aFCU53_23990Not AvailableNegative4943894 - 494443320791.3
upf0259 family proteinFCU53_23995Not AvailableNegative4944463 - 494520626406.5
outer membrane protein ompwFCU53_24005Not AvailablePositive4945563 - 494620122924.2
integraseFCU53_24010Not AvailableNegative4946247 - 494737743169.1
excisionaseFCU53_24015Not AvailableNegative4947355 - 49476039211.41
exonucleaseFCU53_24020Not AvailableNegative4947668 - 495013992405.3
duf1482 family proteinFCU53_24025Not AvailableNegative4950232 - 49504236797.19
cell division inhibition protein dicbFCU53_24030Not AvailableNegative4950420 - 49506087100.74

Displaying genes 4681 – 4690 of 4873 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total