Escherichia coli strain SIEC015 16_NODE_101

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SIEC015 16_NODE_101 is a Gram-negative, rod-shaped bacterium that is facultative anaerobic and exhibits mobility due to the presence of flagella. It typically arranges itself in pairs or as single cells and thrives optimally at 37°C, classifying it as mesophilic. This strain is characterized by having a single replicon and two membranes. SIEC015 is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others. It interacts with a diverse range of organisms, spanning multiple taxa such as mammals, birds, amphibians, and plants, highlighting its ecological versatility. This strain is notable for its pathogenic potential in humans, being linked to several health complications. It is associated with urinary tract infections (UTIs), gastrointestinal infections, and various severe conditions such as neonatal meningitis, septicemia, and hemolytic uremic syndrome (HUS). The bacterium can cause both diarrheal diseases and colibacillosis, leading to significant health concerns, particularly in vulnerable populations. The diverse array of hosts and the multitude of diseases associated with E. coli strain SIEC015 underscore its ecological and biological significance. Its ability to thrive in various environments and its pathogenicity reinforce the importance of monitoring this strain in both clinical and environmental contexts to mitigate health risks associated with its infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain SIEC015 16_NODE_101

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain SIEC015 16_NODE_101
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SIEC015 16_NODE_101, whole genome shotgun

Gene Summary

Adenine Count

1325611 bp

Thymine Count

1319950 bp

Guanine Count

1317451 bp

Cytosine Count

1366835 bp

Genome Length

5329847 bp

Protein-coding Genes

4868 genes

Non-Coding Genes

285 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
isochorismate synthase entcFCU54_09265Not AvailableNegative1903165 - 190434042903.0
fe2+-enterobactin abc transporter substrate-binding proteinFCU54_09270Not AvailablePositive1904529 - 190548534313.1
enterobactin transporter entsFCU54_09275Not AvailableNegative1905489 - 190673943335.9
fe(3+)-siderophore abc transporter permeaseFCU54_09280Not AvailablePositive1906850 - 190785433851.5
iron-enterobactin abc transporter permeaseFCU54_09285Not AvailablePositive1907851 - 190884334954.5
iron-enterobactin abc transporter atp-binding proteinFCU54_09290Not AvailablePositive1908840 - 190965529812.0
lps o-antigen length regulatorFCU54_09295Not AvailableNegative1909652 - 191078542163.8
enterobactin non-ribosomal peptide synthetase entfFCU54_09300Not AvailableNegative1911000 - 1914881142154.0
mbth family proteinFCU54_09305Not AvailableNegative1914878 - 19150968341.73
enterochelin esteraseFCU54_09310Not AvailableNegative1915099 - 191630145513.9

Displaying genes 1931 – 1940 of 5153 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total