Klebsiella pneumoniae strain SIKP010 11_NODE_87

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP010 (accession SWMC00000000.1) is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic respiration and is classified as a chemoheterotroph, utilizing organic compounds as its energy source. This strain is notable for its mobility, attributed to the presence of flagella, and it typically arranges itself in chains, pairs, and singles. The optimal growth temperature for SIKP010 is 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and is characterized by a double-membrane structure, which is typical of Gram-negative bacteria. SIKP010 is known to have a free-living biotic relationship, yet it is also associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other animals and plants. Clinically, this strain is significant due to its pathogenicity in humans, being associated with a variety of infections such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The ability of Klebsiella pneumoniae to cause a diverse array of health issues underscores its role as a notable pathogen in medical microbiology. Ecologically, the ability of SIKP010 to inhabit various host species suggests it may play a complex role in microbial communities, potentially influencing health and disease dynamics in both humans and animals. Its free-living nature may also allow it to adapt and survive in various environments, contributing to its persistence and pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP010 11_NODE_87

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP010 11_NODE_87
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP010 11_NODE_87


Gene Summary

Adenine Count

1164755 bp

Thymine Count

1165077 bp

Guanine Count

1555276 bp

Cytosine Count

1572392 bp

Genome Length

5457500 bp

Protein-coding Genes

5045 genes

Non-Coding Genes

334 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-forming cellulose synthase catalytic subunitFCV02_03770Not AvailablePositive764232 - 76685099289.2
cellulose biosynthesis cyclic di-gmp-binding regulatory protein bcsbFCV02_03775Not AvailablePositive766861 - 76920686102.6
cellulaseFCV02_03780Not AvailablePositive769210 - 77031940932.4
cellulose biosynthesis protein bcscFCV02_03785Not AvailablePositive770301 - 773780127008.0
biofilm formation regulator hmspFCV02_03790Not AvailablePositive773999 - 77602976073.5
dicarboxylate/amino acid:cation symporterFCV02_03795Not AvailablePositive776186 - 77747245373.0
insulinase family proteinFCV02_03800Not AvailablePositive777692 - 77919455758.5
sugar kinaseFCV02_03805Not AvailableNegative779249 - 78017833957.1
antibiotic biosynthesis monooxygenaseFCV02_03810Not AvailableNegative780171 - 7803566983.3
asma family proteinFCV02_03815Not AvailablePositive780373 - 78242474316.7

Displaying genes 1021 – 1030 of 5379 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total