Escherichia coli strain SIEC035 36_NODE_137

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SIEC035 36_NODE_137 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for colonization in warm-blooded hosts. The strain has been identified in a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and many others across various taxa, indicating its ecological versatility. This free-living bacterium can also interact with diverse organisms, including other vertebrates and plants, such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). The wide array of hosts suggests that SIEC035 has adapted to various ecological niches, potentially influencing microbial communities in these environments. Clinically, E. coli strain SIEC035 is known to be pathogenic to humans, associated with numerous health issues including urinary tract infections (UTIs), gastrointestinal infections, septicemia, and neonatal meningitis. These health effects underscore the strain's potential impact on public health and the importance of monitoring its presence in both clinical and environmental settings. The extensive list of diseases linked to this strain highlights its role in human health, particularly in relation to enteric diseases and infections affecting the urinary tract, which necessitates further investigation into its pathogenic mechanisms and ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain SIEC035 36_NODE_137

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain SIEC035 36_NODE_137
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SIEC035 36_NODE_137, whole genome shotgun

Gene Summary

Adenine Count

1175622 bp

Thymine Count

1172987 bp

Guanine Count

1214717 bp

Cytosine Count

1200363 bp

Genome Length

4763689 bp

Protein-coding Genes

4325 genes

Non-Coding Genes

225 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinFCU15_22415Not AvailablePositive4592373 - 45925888289.44
hypothetical proteinFCU15_22420Not AvailableNegative4592744 - 45928042293.74
multidrug efflux rnd transporter permease subunit acrfFCU15_22430Not AvailablePositive4593856 - 4596960111461.0
hypothetical proteinFCU15_22435Not AvailablePositive4597213 - 45974347452.14
amino acid abc transporter substrate-binding proteinFCU15_22440Not AvailablePositive4597865 - 459889037048.9
amino acid abc transporter permeaseFCU15_22445Not AvailablePositive4598958 - 460013943263.9
amino acid abc transporter permeaseFCU15_22450Not AvailablePositive4600149 - 460125241486.7
amino acid abc transporter atp-binding proteinFCU15_22455Not AvailablePositive4601260 - 460201828575.9
is4 family transposaseFCU15_22465Not AvailableNegative4602328 - 460260310113.1
type i toxin-antitoxin system hok family toxinFCU15_22470Not AvailableNegative4602680 - 46028325559.11

Displaying genes 4361 – 4370 of 4550 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total