Klebsiella pneumoniae strain 1811130032 blood API 5215773

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 1811130032 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is notable for its ability to move, facilitated by the presence of flagella, and typically grows in a mesophilic temperature range, with an optimal growth temperature of 37°C. The cells are arranged in chains, pairs, and singles, indicating a versatile cellular organization. This bacterium is primarily host-associated, with a diverse range of hosts including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and plants. Its pathogenicity is significant in humans, where it is linked to numerous health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause a wide range of infections, including severe conditions like meningitis and liver abscesses, underscores its clinical importance. Klebsiella pneumoniae strain 1811130032 has a single replicon and possesses two membranes, which is characteristic of Gram-negative bacteria. As a free-living organism, it plays a complex role in both environmental and clinical settings. Its ability to infect multiple hosts and cause a variety of diseases highlights the importance of monitoring this strain for public health. Understanding its ecological interactions and pathogenic mechanisms is crucial for developing effective treatment and prevention strategies against its associated infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 1811130032 blood API 5215773

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 1811130032 blood API 5215773
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 1811130032 blood API 5215773

Gene Summary

Adenine Count

1145768 bp

Thymine Count

1153486 bp

Guanine Count

1565330 bp

Cytosine Count

1537369 bp

Genome Length

5401953 bp

Protein-coding Genes

5059 genes

Non-Coding Genes

275 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl-coa carboxylase biotin carboxylase subunitFCG39_24730Not AvailableNegative4960844 - 496219349317.6
acetyl-coa carboxylase biotin carboxyl carrier proteinFCG39_24735Not AvailableNegative4962204 - 496267116467.9
type ii 3-dehydroquinate dehydrataseFCG39_24740Not AvailableNegative4962694 - 496314616429.7
protein-methionine-sulfoxide reductase heme-binding subunit msrqFCG39_24745Not AvailableNegative4963370 - 496397823437.6
protein-methionine-sulfoxide reductase catalytic subunit msrpFCG39_24750Not AvailableNegative4963978 - 496497937102.7
hypothetical proteinFCG39_24755Not AvailablePositive4965207 - 49653987756.46
rnase e specificity factor csrdFCG39_24760Not AvailablePositive4965478 - 496741873390.2
rod shape-determining proteinFCG39_24765Not AvailablePositive4967724 - 496876736954.7
rod shape-determining protein mrecFCG39_24770Not AvailablePositive4968838 - 496983035909.7
rod shape-determining protein mredFCG39_24775Not AvailablePositive4969830 - 497031818661.6

Displaying genes 4881 – 4890 of 5334 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total