Klebsiella pneumoniae strain 1811130034 cecum API 5215773

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 1811130034, identified as a facultative anaerobic, rod-shaped, Gram-negative bacterium, demonstrates notable pathogenicity in humans. This strain is a chemoheterotroph, utilizing organic compounds as energy sources, and is capable of mobility due to the presence of flagella. It typically forms chains, pairs, or singles, contributing to its adaptability in various environments. The habitat of this strain is primarily host-associated, with a diverse range of potential hosts including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. It thrives optimally at 37°C, fitting within a mesophilic temperature range. The strain possesses a single replicon and two membranes, a characteristic feature of Gram-negative bacteria. Klebsiella pneumoniae strain 1811130034 is associated with a wide array of health complications, including but not limited to urinary tract infections, pneumonia, bacteremia, and sepsis. These conditions highlight the strain's significant role in human health, particularly in hospital settings where it can lead to serious infections like pyogenic liver abscesses and neonatal sepsis. The ecological significance of this strain lies in its ability to exist as a free-living organism while simultaneously being a potent pathogen. This duality underscores its adaptability and resilience, allowing it to thrive in diverse environments and interact with various host organisms. Understanding its traits and pathogenic potential is crucial for managing its impact on human health and preventing associated infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 1811130034 cecum API 5215773

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 1811130034 cecum API 5215773
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 1811130034 cecum API 5215773

Gene Summary

Adenine Count

1151573 bp

Thymine Count

1153296 bp

Guanine Count

1568841 bp

Cytosine Count

1539337 bp

Genome Length

5413047 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-arg;Not AvailableNot AvailablePositive90204 - 90280Not Available
Hypothetical proteinFCG37_00425Not AvailableNegative90467 - 906255699.97
Trna-arg;Not AvailableNot AvailablePositive90431 - 90507Not Available
Trna-ser;Not AvailableNot AvailablePositive90512 - 90604Not Available
Hypothetical proteinFCG37_00430Not AvailableNegative90618 - 9091110929.2
Putative transcriptional regulatorFCG37_00435Not AvailableNegative91021 - 912699436.33
Putative rect family proteinFCG37_00440Not AvailableNegative91318 - 9219932106.2
Putative exodeoxyribonucleaseFCG37_00445Not AvailableNegative92196 - 9301731413.1
Hypothetical proteinFCG37_00450Not AvailableNegative93303 - 9360211692.0
Putative repressorFCG37_00455Not AvailableNegative93967 - 9454821633.6

Displaying genes 11 – 20 of 5341 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total