Klebsiella pneumoniae strain 1811260006 lung abscess API 7215773

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 1811260006 is a significant pathogen associated with various health complications in humans and other organisms. This Gram-negative bacterium exhibits a rod shape and can be found in diverse arrangements, including chains, pairs, and singles. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, indicating its mesophilic nature. This strain is capable of mobility, possessing flagella, and relies on chemoheterotrophic metabolism for energy. It has a biotic relationship characterized as free-living, and it is primarily associated with hosts such as Homo sapiens, Gallus gallus, and various other metazoans, including mammals and birds. Klebsiella pneumoniae strain 1811260006 is linked to a wide range of health issues, including pneumonia, urinary tract infections, bacteremia, and liver abscesses. Its pathogenicity is particularly notable in humans, where it can lead to severe conditions such as sepsis, meningitis, and pulmonary infections. The strain's ability to cause infections in different hosts underscores its ecological versatility and the potential for zoonotic transmission. The presence of this bacterium in both clinical and environmental contexts highlights its significance as a pathogen, necessitating ongoing monitoring and research to understand its epidemiology and the mechanisms behind its pathogenicity.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 1811260006 lung abscess API 7215773

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 1811260006 lung abscess API 7215773
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 1811260006 lung abscess API 7215773

Gene Summary

Adenine Count

1154126 bp

Thymine Count

1152262 bp

Guanine Count

1563995 bp

Cytosine Count

1545979 bp

Genome Length

5416362 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

240 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphomethylpyrimidine synthase thicFCG28_24860Not AvailablePositive4982580 - 498447570775.2
thiamine phosphate synthaseFCG28_24865Not AvailablePositive4984475 - 498511023016.6
hesa/moeb/thif family proteinFCG28_24870Not AvailablePositive4985103 - 498585827031.9
sulfur carrier protein thisFCG28_24875Not AvailablePositive4985842 - 49860427436.88
thiazole synthaseFCG28_24880Not AvailablePositive4986044 - 498681426788.8
2-iminoacetate synthase thihFCG28_24885Not AvailablePositive4986811 - 498794443099.4
diguanylate cyclaseFCG28_24890Not AvailablePositive4988261 - 498979358031.6
pts sugar transporter subunit iibFCG28_24895Not AvailablePositive4989966 - 499027110905.7
pts lactose/cellobiose transporter subunit iiaFCG28_24900Not AvailablePositive4990275 - 499059211539.1
anaerobic c4-dicarboxylate transporterFCG28_24905Not AvailableNegative4990635 - 499197547895.1

Displaying genes 4881 – 4890 of 5323 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total