Klebsiella pneumoniae strain SIKP185 N21_NODE_79

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP185 N21_NODE_79 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, categorizing it as a chemoheterotroph. This strain is notable for its ability to form chains, pairs, and singles in its cell arrangement. It possesses flagella, which contribute to its mobility, and thrives optimally at 37°C, indicating its mesophilic nature. This strain is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan species, as well as plants and aquatic organisms. Its biotic relationship is classified as free-living, suggesting it can exist independently in various environments while also having potential interactions with host organisms. Klebsiella pneumoniae SIKP185 is associated with a significant number of health effects in humans, including but not limited to bacteremia, urinary tract infections, pneumonia, and sepsis. The bacterium is implicated in severe conditions, such as pyogenic liver abscess and neonatal sepsis, indicating its pathogenicity and relevance in clinical microbiology. The presence of a single replicon and two membranes is characteristic of its cellular structure, which is typical for Gram-negative bacteria. The diverse host range and the variety of associated diseases highlight the ecological versatility and potential impact of Klebsiella pneumoniae strain SIKP185 in both environmental and clinical contexts. Understanding the characteristics of this strain can inform strategies for managing infections it may cause in humans and other hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP185 N21_NODE_79

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP185 N21_NODE_79
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP185 N21_NODE_79, whole genome

Gene Summary

Adenine Count

1182288 bp

Thymine Count

1178896 bp

Guanine Count

1578032 bp

Cytosine Count

1582678 bp

Genome Length

5521894 bp

Protein-coding Genes

5137 genes

Non-Coding Genes

317 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative coat proteinFAU14_04650Not AvailableNegative915557 - 91661239412.5
Putative capsid decoration proteinFAU14_04655Not AvailableNegative916609 - 91707015663.9
Hypothetical proteinFAU14_04660Not AvailableNegative917070 - 91842549373.3
hypothetical proteinFAU14_04665Not AvailablePositive918476 - 9186797563.12
Phage head morphogenesisFAU14_04670Not AvailableNegative918676 - 91968938178.8
Portal proteinFAU14_04675Not AvailableNegative919607 - 92105553615.6
Terminase large subunitFAU14_04680Not AvailableNegative921067 - 92263559303.0
Terminase small subunitFAU14_04685Not AvailableNegative922632 - 92328224335.9
EndopeptidaseFAU14_04690Not AvailableNegative923491 - 92395816664.9
LysinFAU14_04695Not AvailableNegative923955 - 92445818385.3

Displaying genes 31 – 40 of 5454 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total