Klebsiella pneumoniae strain SIKP184 N20_NODE_82

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP184 N20_NODE_82 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is capable of thriving in a host-associated habitat, reflecting its adaptability to various biological environments. It exhibits mobility, possessing flagella, and typically forms chains, pairs, or singles. The bacterium has a mesophilic temperature range, with an optimal growth temperature of 37°C, making it well-suited to the warm conditions found in many hosts. It has a unique cellular structure characterized by two membranes and a single replicon, which is typical for members of the Enterobacteriaceae family. K. pneumoniae strain SIKP184 has a broad range of biotic relationships, being free-living while also infecting various hosts, including Homo sapiens, Gallus gallus, and other metazoans and plants. The strain is associated with a significant number of health effects. It is known to cause infections such as bacteremia, urinary tract infections, pneumonia, and more severe conditions like sepsis and meningitis. The pathogenicity of this strain highlights its potential impact on both human health and veterinary medicine, emphasizing its role as a significant opportunistic pathogen. The diverse range of hosts it can infect suggests that K. pneumoniae strain SIKP184 plays a complex ecological role, potentially influencing the health of various species and contributing to the dynamics of microbial communities in host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP184 N20_NODE_82

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP184 N20_NODE_82
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP184 N20_NODE_82, whole genome

Gene Summary

Adenine Count

1174798 bp

Thymine Count

1184754 bp

Guanine Count

1583728 bp

Cytosine Count

1575063 bp

Genome Length

5518343 bp

Protein-coding Genes

5131 genes

Non-Coding Genes

312 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multifunctional cca addition/repair proteinFAU13_05890Not AvailableNegative1191075 - 119231645988.4
sh3 domain-containing proteinFAU13_05895Not AvailableNegative1192378 - 119299823098.7
inorganic triphosphataseFAU13_05900Not AvailablePositive1193213 - 119451148303.8
bifunctionalFAU13_05905Not AvailablePositive1194535 - 1197369107371.0
bifunctional d-glycero-beta-d-manno-heptose-7-phosphate kinase/d-glycero-beta-d-manno-heptose 1-phosphate adenylyltransferase hldeFAU13_05910Not AvailablePositive1197428 - 119886151154.6
cell surface composition regulator glgsFAU13_05915Not AvailablePositive1199080 - 11992777755.08
accessory factor ubik family proteinFAU13_05920Not AvailableNegative1199313 - 119958510477.6
3,4-dihydroxy-2-butanone-4-phosphate synthaseFAU13_05925Not AvailablePositive1199963 - 120061623448.9
zinc transporter zuptFAU13_05930Not AvailableNegative1200678 - 120144826336.3
4,5-dopa dioxygenase extradiolFAU13_05935Not AvailablePositive1201635 - 120242628989.8

Displaying genes 1361 – 1370 of 5443 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total