Klebsiella pneumoniae strain SIKP183 N19_NODE_87

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP183 N19_NODE_87 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. As a chemoheterotroph, it derives energy from organic compounds, making it well-suited to inhabit host-associated environments. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. Optimal growth occurs at 37°C, placing this strain within the mesophilic temperature range. K. pneumoniae SIKP183 has a single replicon and is characterized by a double-membrane structure typical of Gram-negative bacteria. Its biotic relationship is classified as free-living, although it has a significant association with a wide range of hosts, including Homo sapiens, Gallus gallus, and several other vertebrates. This strain is notable for its pathogenic potential in humans, being implicated in a variety of health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The diverse range of diseases associated with K. pneumoniae underscores its role as a significant opportunistic pathogen. Ecologically, the presence of K. pneumoniae in various hosts suggests it can adapt to multiple environments, potentially facilitating its transmission and persistence in both human and animal populations. Understanding the dynamics of this strain in host-associated habitats can provide insights into its pathogenic mechanisms and inform strategies for managing infections caused by K. pneumoniae.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP183 N19_NODE_87

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP183 N19_NODE_87
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP183 N19_NODE_87, whole genome

Gene Summary

Adenine Count

1176250 bp

Thymine Count

1177260 bp

Guanine Count

1576808 bp

Cytosine Count

1572444 bp

Genome Length

5502762 bp

Protein-coding Genes

5119 genes

Non-Coding Genes

313 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphogluconate dehydrataseFAU16_16985Not AvailablePositive3460759 - 346257064571.0
bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolaseFAU16_16990Not AvailablePositive3462609 - 346325022230.1
formate-dependent phosphoribosylglycinamide formyltransferaseFAU16_16995Not AvailableNegative3463308 - 346448641958.5
lexa family transcriptional regulatorFAU16_17000Not AvailablePositive3464631 - 346497812602.0
tellurite resistance terb family proteinFAU16_17005Not AvailablePositive3465118 - 346577723235.6
oligopeptidase bFAU16_17010Not AvailablePositive3465898 - 346795878926.0
exodeoxyribonuclease xFAU16_17015Not AvailableNegative3467962 - 346862125003.3
dna polymerase iii subunit thetaFAU16_17020Not AvailableNegative3468700 - 34689308871.7
copc domain-containing protein yobaFAU16_17025Not AvailablePositive3469043 - 346941712845.4
copper homeostasis membrane protein copdFAU16_17030Not AvailablePositive3469421 - 347029031496.7

Displaying genes 3531 – 3540 of 5432 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total