Klebsiella pneumoniae strain SIKP179 N15_NODE_81

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP179 N15_NODE_81 is a Gram-negative, rod-shaped bacterium that demonstrates facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain exhibits a diverse habitat, being host-associated and capable of free-living biotic relationships. It is characterized by its mobility, facilitated by the presence of flagella, and typically forms chains, pairs, or singles. With an optimal growth temperature of 37°C, SIKP179 falls within the mesophilic temperature range. The organism possesses one replicon and two membranes, which is typical for this bacterial genus. Its pathogenicity is notably significant in humans, as it is associated with a wide array of health complications including bacteremia, urinary tract infections, pneumonia, and various types of abscesses, among others. The strain has been documented to infect multiple hosts, including Homo sapiens, domestic animals like Gallus gallus (chickens) and Sus scrofa (pigs), as well as various species across Metazoa, Viridiplantae, and Danio rerio (zebrafish). This broad host range underscores its ecological versatility and potential for transmission between species. The health impacts of Klebsiella pneumoniae strain SIKP179 highlight its role as an opportunistic pathogen in hospital settings, particularly in immunocompromised individuals. Understanding the traits of this strain can provide insights into its ecological adaptations and the challenges it poses in clinical microbiology, particularly its capacity for causing severe infections in multiple host organisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP179 N15_NODE_81

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP179 N15_NODE_81
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP179 N15_NODE_81, whole genome

Gene Summary

Adenine Count

1182864 bp

Thymine Count

1178249 bp

Guanine Count

1571308 bp

Cytosine Count

1589310 bp

Genome Length

5521731 bp

Protein-coding Genes

5101 genes

Non-Coding Genes

349 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rok family proteinFAU19_11595Not AvailableNegative2391751 - 239297144349.9
n-acetylglucosamine-6-phosphate deacetylaseFAU19_11600Not AvailableNegative2392980 - 239412841289.7
glucosamine-6-phosphate deaminaseFAU19_11605Not AvailableNegative2394242 - 239504229685.9
pts n-acetyl glucosamine transporter subunit iiabcFAU19_11610Not AvailablePositive2395357 - 239731268143.7
glutamine--trna ligaseFAU19_11615Not AvailablePositive2397491 - 239915863615.2
methionine synthaseFAU19_11620Not AvailableNegative2399212 - 239952011943.8
chitoporinFAU19_11625Not AvailablePositive2399594 - 240099752334.5
hypothetical proteinFAU19_11630Not AvailablePositive2401045 - 240137712255.7
mfs transporterFAU19_11635Not AvailableNegative2401374 - 240194320510.5
ferric iron uptake transcriptional regulatorFAU19_11640Not AvailableNegative2401993 - 240244517110.2

Displaying genes 2561 – 2570 of 5450 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total