Klebsiella pneumoniae strain SIKP178 N14_NODE_90

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP178 N14_NODE_90 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It typically thrives at an optimal temperature of 37°C and is classified as mesophilic, allowing it to inhabit a variety of warm-blooded hosts, including Homo sapiens, Gallus gallus, and other metazoans. This strain possesses flagella, indicating motility, and can be found in various cellular arrangements such as chains, pairs, and singles. K. pneumoniae is known for its significant pathogenicity in humans, being associated with numerous health concerns including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its environmental presence is linked to a free-living biotic relationship, although it primarily relies on hosts for survival and proliferation. With a single replicon and a double membrane structure, the bacterium demonstrates typical characteristics of the Enterobacteriaceae family. The wide range of hosts it can infect—from mammals to birds and amphibians—highlights its ecological versatility and potential for zoonotic transmission. Klebsiella pneumoniae strain SIKP178 N14_NODE_90's ability to cause severe infections in multiple host species underscores the importance of monitoring this pathogen in clinical and environmental settings, given its implications for public health and its role in disease dynamics across various ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP178 N14_NODE_90

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP178 N14_NODE_90
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP178 N14_NODE_90, whole genome

Gene Summary

Adenine Count

1171989 bp

Thymine Count

1181886 bp

Guanine Count

1594049 bp

Cytosine Count

1559022 bp

Genome Length

5506946 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinFAU06_21840Not AvailableNegative4410350 - 441090421133.7
siderophore yersiniabactin receptor fyuaFAU06_21850Not AvailableNegative4412147 - 441416873687.1
yersiniabactin biosynthesis salycil-amp ligase ybteFAU06_21855Not AvailableNegative4414299 - 441587657226.5
yersiniabactin biosynthesis thioesterase ybttFAU06_21860Not AvailableNegative4415880 - 441668329714.4
yersiniabactin biosynthesis oxidoreductase ybtuFAU06_21865Not AvailableNegative4416680 - 441778040915.2
yersiniabactin polyketide synthase hmwp1FAU06_21870Not AvailableNegative4417777 - 4427268348747.0
yersiniabactin non-ribosomal peptide synthetase hmwp2FAU06_21875Not AvailableNegative4427356 - 4433463228666.0
yersiniabactin transcriptional regulator ybtaFAU06_21880Not AvailableNegative4433654 - 443461335865.1
yersiniabactin abc transporter atp-binding/permease protein ybtpFAU06_21885Not AvailablePositive4434780 - 443658266288.9
yersiniabactin abc transporter atp-binding/permease protein ybtqFAU06_21890Not AvailablePositive4436569 - 443837166495.5

Displaying genes 4401 – 4410 of 5442 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total