Klebsiella pneumoniae strain SIKP178 N14_NODE_90

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP178 N14_NODE_90 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It typically thrives at an optimal temperature of 37°C and is classified as mesophilic, allowing it to inhabit a variety of warm-blooded hosts, including Homo sapiens, Gallus gallus, and other metazoans. This strain possesses flagella, indicating motility, and can be found in various cellular arrangements such as chains, pairs, and singles. K. pneumoniae is known for its significant pathogenicity in humans, being associated with numerous health concerns including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its environmental presence is linked to a free-living biotic relationship, although it primarily relies on hosts for survival and proliferation. With a single replicon and a double membrane structure, the bacterium demonstrates typical characteristics of the Enterobacteriaceae family. The wide range of hosts it can infect—from mammals to birds and amphibians—highlights its ecological versatility and potential for zoonotic transmission. Klebsiella pneumoniae strain SIKP178 N14_NODE_90's ability to cause severe infections in multiple host species underscores the importance of monitoring this pathogen in clinical and environmental settings, given its implications for public health and its role in disease dynamics across various ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP178 N14_NODE_90

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP178 N14_NODE_90
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP178 N14_NODE_90, whole genome

Gene Summary

Adenine Count

1171989 bp

Thymine Count

1181886 bp

Guanine Count

1594049 bp

Cytosine Count

1559022 bp

Genome Length

5506946 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hth-type transcriptional activator rhasFAU06_18760Not AvailablePositive3831524 - 383236032002.9
hth-type transcriptional activator rharFAU06_18765Not AvailablePositive3832434 - 383327932207.5
l-rhamnose/proton symporter rhatFAU06_18770Not AvailableNegative3833312 - 383434637162.9
superoxide dismutaseFAU06_18775Not AvailablePositive3834636 - 383525622986.0
6-n-hydroxylaminopurine resistance proteinFAU06_18780Not AvailablePositive3835329 - 383600325211.8
envelope stress sensor histidine kinase cpxaFAU06_18785Not AvailableNegative3836071 - 383744451733.3
envelope stress response regulator transcription factor cpxrFAU06_18790Not AvailableNegative3837441 - 383813926273.7
cell-envelope stress modulator cpxpFAU06_18795Not AvailablePositive3838289 - 383879218865.6
cation-efflux pump fiefFAU06_18800Not AvailablePositive3838951 - 383985332888.0
atp-dependent 6-phosphofructokinaseFAU06_18805Not AvailablePositive3840050 - 384101234986.4

Displaying genes 3901 – 3910 of 5442 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total