Klebsiella pneumoniae strain SIKP178 N14_NODE_90

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP178 N14_NODE_90 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It typically thrives at an optimal temperature of 37°C and is classified as mesophilic, allowing it to inhabit a variety of warm-blooded hosts, including Homo sapiens, Gallus gallus, and other metazoans. This strain possesses flagella, indicating motility, and can be found in various cellular arrangements such as chains, pairs, and singles. K. pneumoniae is known for its significant pathogenicity in humans, being associated with numerous health concerns including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its environmental presence is linked to a free-living biotic relationship, although it primarily relies on hosts for survival and proliferation. With a single replicon and a double membrane structure, the bacterium demonstrates typical characteristics of the Enterobacteriaceae family. The wide range of hosts it can infect—from mammals to birds and amphibians—highlights its ecological versatility and potential for zoonotic transmission. Klebsiella pneumoniae strain SIKP178 N14_NODE_90's ability to cause severe infections in multiple host species underscores the importance of monitoring this pathogen in clinical and environmental settings, given its implications for public health and its role in disease dynamics across various ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP178 N14_NODE_90

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP178 N14_NODE_90
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP178 N14_NODE_90, whole genome

Gene Summary

Adenine Count

1171989 bp

Thymine Count

1181886 bp

Guanine Count

1594049 bp

Cytosine Count

1559022 bp

Genome Length

5506946 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lps export abc transporter permease lptgFAU06_17105Not AvailablePositive3473801 - 347488339632.1
duf853 domain-containing proteinFAU06_17110Not AvailableNegative3474932 - 347643454153.2
inosose isomeraseFAU06_17115Not AvailableNegative3476533 - 347735430601.7
coa-acylating methylmalonate-semialdehyde dehydrogenaseFAU06_17120Not AvailablePositive3477706 - 347921153598.3
5-deoxy-glucuronate isomeraseFAU06_17125Not AvailablePositive3479230 - 348003930457.8
aspartate 1-decarboxylase autocleavage activator panmFAU06_17130Not AvailableNegative3480415 - 348079814588.4
hypothetical proteinFAU06_17135Not AvailableNegative3481047 - 34811905520.03
high-affinity branched-chain amino acid abc transporter substrate-binding protein livkFAU06_17140Not AvailablePositive3481222 - 348233139443.2
high-affinity branched-chain amino acid abc transporter permease livhFAU06_17145Not AvailablePositive3482393 - 348331933014.5
high-affinity branched-chain amino acid abc transporter permease livmFAU06_17150Not AvailablePositive3483316 - 348459346411.4

Displaying genes 3571 – 3580 of 5442 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total