Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is a Gram-negative, rod-shaped bacterium that exhibits a chemoheterotrophic metabolism, utilizing organic compounds as energy sources. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and low-oxygen environments. It is capable of mobility due to the presence of flagella, and it typically exists in diverse arrangements, including chains, pairs, and singles. The optimal growth temperature for SIKP168 is 37°C, aligning with the mesophilic temperature range that supports its biological processes. This strain possesses a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. As a free-living organism, it has established biotic relationships that allow it to persist in host-associated habitats. Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is clinically significant due to its association with pneumonia, particularly community-acquired pneumonia (CAP), highlighting its role in human health. Given its pathogenic potential, understanding the ecological and biological traits of this strain is vital for developing strategies to mitigate its impact on public health. The strain's adaptability and survival mechanisms underscore its relevance in both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP168

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP168
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gene Summary

Adenine Count

1180039 bp

Thymine Count

1184434 bp

Guanine Count

1578323 bp

Cytosine Count

1586219 bp

Genome Length

5529015 bp

Protein-coding Genes

5144 genes

Non-Coding Genes

323 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cytochrome b561FAT87_01350Not AvailablePositive256348 - 25687520135.5
metal/formaldehyde-sensitive transcriptional repressorFAT87_01355Not AvailablePositive256980 - 25725510136.3
s-(hydroxymethyl)glutathione dehydrogenase/class iii alcohol dehydrogenaseFAT87_01360Not AvailablePositive257280 - 25839839272.3
membrane-bound pqq-dependent dehydrogenase, glucose/quinate/shikimate familyFAT87_01365Not AvailableNegative258468 - 26084085037.3
lysr family transcriptional regulatorFAT87_01370Not AvailableNegative261141 - 26206433166.7
protocatechuate 3,4-dioxygenase subunit alphaFAT87_01375Not AvailableNegative262242 - 26286223121.3
protocatechuate 3,4-dioxygenase subunit betaFAT87_01380Not AvailableNegative262859 - 26359927893.2
voc family proteinFAT87_01385Not AvailablePositive263839 - 26518250718.3
carboxylesterase/lipase family proteinFAT87_01390Not AvailablePositive265224 - 26672955119.1
nad(p)-dependent alcohol dehydrogenaseFAT87_01395Not AvailableNegative266776 - 26786437553.7

Displaying genes 541 – 550 of 5467 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total