Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is a Gram-negative, rod-shaped bacterium that exhibits a chemoheterotrophic metabolism, utilizing organic compounds as energy sources. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and low-oxygen environments. It is capable of mobility due to the presence of flagella, and it typically exists in diverse arrangements, including chains, pairs, and singles. The optimal growth temperature for SIKP168 is 37°C, aligning with the mesophilic temperature range that supports its biological processes. This strain possesses a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. As a free-living organism, it has established biotic relationships that allow it to persist in host-associated habitats. Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is clinically significant due to its association with pneumonia, particularly community-acquired pneumonia (CAP), highlighting its role in human health. Given its pathogenic potential, understanding the ecological and biological traits of this strain is vital for developing strategies to mitigate its impact on public health. The strain's adaptability and survival mechanisms underscore its relevance in both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP168

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP168
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gene Summary

Adenine Count

1180039 bp

Thymine Count

1184434 bp

Guanine Count

1578323 bp

Cytosine Count

1586219 bp

Genome Length

5529015 bp

Protein-coding Genes

5144 genes

Non-Coding Genes

323 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glucose-6-phosphate isomeraseFAT87_22550Not AvailableNegative4593734 - 459538361331.7
lysine-sensitive aspartokinase 3FAT87_22565Not AvailablePositive4596148 - 459749748434.4
ketopantoate/pantoate/pantothenate transporter pansFAT87_22570Not AvailablePositive4597636 - 459856532700.5
duf3811 domain-containing proteinFAT87_22575Not AvailablePositive4598682 - 459895410544.6
23s rrna pseudouridine(2604) synthase rlufFAT87_22580Not AvailableNegative4598951 - 459982632584.5
dipeptidase pepeFAT87_22585Not AvailablePositive4600025 - 460071424459.7
na/pi cotransporter family proteinFAT87_22590Not AvailableNegative4600827 - 460245859424.5
methionine synthaseFAT87_22595Not AvailableNegative4602588 - 4606271135804.0
glyoxylate bypass operon transcriptional repressor iclrFAT87_22600Not AvailablePositive4606466 - 460729629792.0
bifunctional isocitrate dehydrogenase kinase/phosphataseFAT87_22605Not AvailableNegative4607347 - 460913168888.1

Displaying genes 4571 – 4580 of 5467 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total