Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is a Gram-negative, rod-shaped bacterium that exhibits a chemoheterotrophic metabolism, utilizing organic compounds as energy sources. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and low-oxygen environments. It is capable of mobility due to the presence of flagella, and it typically exists in diverse arrangements, including chains, pairs, and singles. The optimal growth temperature for SIKP168 is 37°C, aligning with the mesophilic temperature range that supports its biological processes. This strain possesses a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. As a free-living organism, it has established biotic relationships that allow it to persist in host-associated habitats. Klebsiella pneumoniae subsp. pneumoniae strain SIKP168 is clinically significant due to its association with pneumonia, particularly community-acquired pneumonia (CAP), highlighting its role in human health. Given its pathogenic potential, understanding the ecological and biological traits of this strain is vital for developing strategies to mitigate its impact on public health. The strain's adaptability and survival mechanisms underscore its relevance in both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP168

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP168
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP168

Gene Summary

Adenine Count

1180039 bp

Thymine Count

1184434 bp

Guanine Count

1578323 bp

Cytosine Count

1586219 bp

Genome Length

5529015 bp

Protein-coding Genes

5144 genes

Non-Coding Genes

323 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
imidazole glycerol phosphate synthase subunit hishFAT87_08070Not AvailablePositive1583784 - 158437421561.1
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseFAT87_08075Not AvailablePositive1584374 - 158511126022.1
imidazole glycerol phosphate synthase subunit hisfFAT87_08080Not AvailablePositive1585093 - 158586928266.8
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieFAT87_08085Not AvailablePositive1585863 - 158645922094.3
n-acetyl-alpha-d-glucosaminyl-diphospho-ditrans, octacis-undecaprenol 3-alpha-mannosyltransferase wbdcFAT87_08090Not AvailableNegative1586498 - 158751438692.2
glycosyltransferase family 1 proteinFAT87_08095Not AvailableNegative1587624 - 158876943872.8
glycosyltransferase family 4 proteinFAT87_08100Not AvailableNegative1588816 - 159133894608.3
methyltransferase domain-containing proteinFAT87_08105Not AvailableNegative1591349 - 159340679448.5
abc transporter atp-binding proteinFAT87_08110Not AvailableNegative1593427 - 159472247916.2
o9 family o-antigen abc transporter permease subunit wzmFAT87_08115Not AvailableNegative1594725 - 159551029737.4

Displaying genes 1771 – 1780 of 5467 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total