Klebsiella pneumoniae strain SIKP167 176_NODE_118

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP167 (176_NODE_118) is a Gram-negative, rod-shaped, facultative anaerobe known for its significant pathogenicity in humans and various animal hosts. This strain exhibits a mobile nature, with flagella present, allowing it to thrive in diverse environments. Its optimal growth temperature is 37°C, categorizing it as mesophilic. In terms of habitat, SIKP167 is associated with hosts, including Homo sapiens and a range of other species such as Gallus gallus, Danio rerio, and Sus scrofa. This broad host range highlights its ecological versatility. As a chemoheterotroph, it relies on organic compounds for energy, further emphasizing its adaptability to different environments. Klebsiella pneumoniae strain SIKP167 is implicated in various health issues, including bacteremia, urinary tract infections, pneumonia, and several other severe conditions such as sepsis and liver abscesses. The strain's ability to cause a wide array of infections underscores its pathogenic potential and poses significant health risks, particularly in immunocompromised individuals. The presence of a single replicon and two membranes indicates its prokaryotic structure, aligning with the characteristics of many pathogenic bacteria. Its nonsporulating nature suggests that SIKP167 may rely on its host environments for survival and replication rather than forming resilient spores. Overall, the ecological insight from SIKP167's traits reveals its capacity to thrive in diverse host-associated environments while posing serious health risks. Its adaptability and pathogenicity highlight the need for continued monitoring and research on Klebsiella pneumoniae to mitigate its impact on human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP167 176_NODE_118

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP167 176_NODE_118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP167 176_NODE_118, whole genome

Gene Summary

Adenine Count

1190037 bp

Thymine Count

1186595 bp

Guanine Count

1592269 bp

Cytosine Count

1587489 bp

Genome Length

5556390 bp

Protein-coding Genes

5158 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinFAT92_17185Not AvailableNegative3535989 - 35361867430.09
Hypothetical proteinFAT92_17190Not AvailableNegative3536324 - 353680617935.3
Putative major tail proteinFAT92_17195Not AvailableNegative3536861 - 353803341022.8
Putative tail terminator proteinFAT92_17200Not AvailableNegative3538057 - 353844914016.7
Hypothetical proteinFAT92_17205Not AvailableNegative3538446 - 353899720185.9
Hypothetical proteinFAT92_17210Not AvailableNegative3538999 - 353938213766.2
hypothetical proteinFAT92_17215Not AvailableNegative3539369 - 35396028573.41
Hypothetical proteinFAT92_17220Not AvailableNegative3539612 - 35398669440.26
Putative head-tail joining proteinFAT92_17225Not AvailableNegative3539868 - 354026314328.0
hypothetical proteinFAT92_17230Not AvailableNegative3540304 - 35405768625.77

Displaying genes 31 – 40 of 5506 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total