Klebsiella pneumoniae subsp. pneumoniae strain SIKP166

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP166 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle. It is chemoheterotrophic, deriving its energy from organic compounds. This strain typically exists in various cellular arrangements, including singles, pairs, and chains, and is characterized by the presence of flagella, which contributes to its mobility. The optimal growth temperature for SIKP166 is 37°C, placing it within the mesophilic temperature range, which is conducive to growth in warm-blooded hosts. As a free-living organism, it can thrive in host-associated habitats, highlighting its adaptability and potential ecological roles. Klebsiella pneumoniae subsp. pneumoniae is notably associated with health implications, particularly in causing pneumonia, including community-acquired pneumonia (CAP). This association underscores the bacterium's significance in clinical settings, where it can lead to serious respiratory infections, especially in vulnerable populations. With a single replicon and two membranes, SIKP166 reflects typical structural characteristics of Gram-negative bacteria. Its nonsporulating nature indicates that it does not form spores as a survival strategy, which may influence its ecological interactions and pathogenicity. The presence of this strain in both free-living and host-associated environments suggests a dual role in the ecosystem, potentially impacting both human health and environmental microbiomes. Understanding its traits can aid in developing strategies for managing infections and recognizing its ecological significance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP166

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP166
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP166

Gene Summary

Adenine Count

1171228 bp

Thymine Count

1177833 bp

Guanine Count

1595472 bp

Cytosine Count

1565178 bp

Genome Length

5509711 bp

Protein-coding Genes

5172 genes

Non-Coding Genes

286 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aminopeptidase nFAU01_09920Not AvailablePositive2023109 - 202572498741.9
aliphatic sulfonates abc transporter atp-binding proteinFAU01_09925Not AvailableNegative2025929 - 202670227926.1
aliphatic sulfonate abc transporter permease ssucFAU01_09930Not AvailableNegative2026699 - 202749028910.1
fmnh2-dependent alkanesulfonate monooxygenaseFAU01_09935Not AvailableNegative2027501 - 202864641833.8
sulfonate abc transporter substrate-binding proteinFAU01_09940Not AvailableNegative2028643 - 202960534274.1
nadph-dependent fmn reductaseFAU01_09945Not AvailableNegative2029598 - 203017321027.2
quinone-dependent dihydroorotate dehydrogenaseFAU01_09950Not AvailablePositive2030423 - 203143336750.9
cell division protein zapcFAU01_09955Not AvailablePositive2031603 - 203214520400.5
mosc domain-containing proteinFAU01_09960Not AvailableNegative2032142 - 203325140427.3
bifunctional 23s rrna (guanine(2069)-n(7))-methyltransferase rlmk/23s rrna (guanine(2445)-n(2))-methyltransferase rlmlFAU01_09965Not AvailablePositive2033351 - 203545678915.6

Displaying genes 2181 – 2190 of 5458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total