Klebsiella pneumoniae strain SIKP190 N26_NODE_108

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP190 N26_NODE_108 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in diverse environments. This strain is classified as a chemoheterotroph, relying on organic compounds as its energy source. It typically exists in a variety of arrangements, including chains, pairs, and singles, and possesses flagella, enabling mobility. The optimal growth temperature for SIKP190 is 37°C, categorizing it as mesophilic, which aligns with typical human body temperature and suggests its adaptation to host-associated habitats. It has a single replicon and a double membrane structure, characteristic of many Gram-negative bacteria. Klebsiella pneumoniae is known for its significant health impacts on various hosts, including humans and several animal species such as Gallus gallus (chickens), Canis lupus familiaris (domestic dogs), and others. It is associated with a wide range of infections, including bacteremia, urinary tract infections, pneumonia, and even severe conditions like sepsis and meningitis. Its pathogenicity primarily affects humans, making it a notable concern in clinical microbiology. The presence of this strain in diverse animal hosts and its ability to cause severe infections highlight its ecological versatility and potential implications for both human and animal health. Understanding the traits and behaviors of Klebsiella pneumoniae strain SIKP190 can provide insights into its role in disease dynamics and the importance of monitoring its spread in various ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP190 N26_NODE_108

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP190 N26_NODE_108
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP190 N26_NODE_108, whole genome

Gene Summary

Adenine Count

1170908 bp

Thymine Count

1177270 bp

Guanine Count

1572252 bp

Cytosine Count

1563863 bp

Genome Length

5484293 bp

Protein-coding Genes

5169 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tn3-like element tn3 family transposaseFAT72_27340Not AvailablePositive5453000 - 545524584568.6
duf4113 domain-containing proteinFAT72_27345Not AvailablePositive5455246 - 545585522777.3
helix-turn-helix transcriptional regulatorFAT72_27350Not AvailableNegative5456002 - 545628310972.2
type ii toxin-antitoxin system rele/pare family toxinFAT72_27355Not AvailableNegative5456264 - 545659312493.4
hypothetical proteinFAT72_27360Not AvailableNegative5457420 - 54574812293.74
duf4158 domain-containing proteinFAT72_27365Not AvailableNegative5457482 - 54576958150.59
recombinase family proteinFAT72_27370Not AvailablePositive5457859 - 545841620604.8
class a broad-spectrum beta-lactamase tem-1FAT72_27375Not AvailablePositive5458599 - 545945931517.0
group ii intron reverse transcriptase/maturaseFAT72_27380Not AvailableNegative5459679 - 546093247783.6
tn3-like element tnas1 family transposaseFAT72_27385Not AvailablePositive5461587 - 546310356803.8

Displaying genes 5311 – 5320 of 5344 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total