Klebsiella pneumoniae strain SIKP186 N22_NODE_81

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP186 N22_NODE_81 is a Gram-negative, rod-shaped bacterium that exhibits a variety of characteristics relevant to its ecological niche and pathogenic potential. This strain is classified as a facultative anaerobe, enabling it to thrive in both aerobic and anaerobic environments. It is a chemoheterotroph, relying on organic compounds for energy, and it typically grows optimally at 37°C, fitting within the mesophilic temperature range. In terms of cellular arrangement, SIKP186 can be found in chains, pairs, or singles, and it possesses flagella, which grants it mobility. The bacterium has a biotic relationship categorized as free-living and is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other animals and plants. Klebsiella pneumoniae is known for its pathogenicity in humans, causing a wide array of health issues such as bacteremia, urinary tract infections, pneumonia, and several other serious conditions. Its ability to infect multiple host species indicates a significant ecological versatility, allowing it to thrive in various environments while also posing a risk to both human and animal health. Given its pathogenic potential and adaptability, Klebsiella pneumoniae strain SIKP186 may play a critical role in the dynamics of host-associated microbial communities, particularly in environments where hosts are in close proximity, such as hospitals or agricultural settings. Understanding its traits can aid in developing strategies for managing infections and mitigating its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP186 N22_NODE_81

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP186 N22_NODE_81
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP186 N22_NODE_81, whole genome

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4796 genes

Non-Coding Genes

654 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l15FAT66_26195Not AvailablePositive5253531 - 525396515135.6
preprotein translocase subunit secyFAT66_26200Not AvailablePositive5253973 - 525530448583.8
50s ribosomal protein l36FAT66_26205Not AvailablePositive5255338 - 52554544364.59
30s ribosomal protein s13FAT66_26210Not AvailablePositive5255601 - 525595713211.4
30s ribosomal protein s11FAT66_26215Not AvailablePositive5255974 - 525636313859.8
30s ribosomal protein s4FAT66_26220Not AvailablePositive5256397 - 525701723503.5
dna-directed rna polymerase subunit alphaFAT66_26225Not AvailablePositive5257043 - 525803236467.9
50s ribosomal protein l17FAT66_26230Not AvailablePositive5258073 - 525845914446.6
duf1992 domain-containing proteinFAT66_26235Not AvailablePositive5258568 - 525893613767.3
zn(2+)-responsive transcriptional regulatorFAT66_26240Not AvailablePositive5258939 - 525936416209.3

Displaying genes 5141 – 5150 of 5450 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total