Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in environments with or without oxygen. This strain is a chemoheterotroph, obtaining energy through the consumption of organic compounds. Its optimal growth temperature is 37°C, classifying it as mesophilic, which aligns with the typical human body temperature, suggesting a close association with human hosts. The bacterial cells are organized in chains, pairs, and singles, contributing to its diverse morphological arrangements. SIKP114 possesses flagella, indicating mobility, which may play a role in its ability to colonize different environments or hosts. Notably, this strain does not form spores, which is characteristic of its genus. Klebsiella pneumoniae subsp. pneumoniae is known to be free-living but is also associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP) in humans. The presence of one replicon and two membranes further highlights its complexity as a bacterium. The ecological insight gained from understanding strain SIKP114 suggests that its adaptability to different oxygen levels and temperature ranges may contribute to its success as a pathogen in human populations. Its mobility and ability to thrive in host-associated environments underscore its role in infectious disease dynamics, particularly in respiratory infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP114

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP114
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gene Summary

Adenine Count

1197434 bp

Thymine Count

1202004 bp

Guanine Count

1597930 bp

Cytosine Count

1605655 bp

Genome Length

5603023 bp

Protein-coding Genes

5220 genes

Non-Coding Genes

269 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tellurite resistance methyltransferase tehbFAT40_14505Not AvailableNegative2956669 - 295726522051.2
dicarboxylate transporter/tellurite-resistance protein tehaFAT40_14510Not AvailableNegative2957262 - 295826636134.9
lbetah domain-containing proteinFAT40_14515Not AvailablePositive2958378 - 295935836020.6
50s ribosomal protein l7/l12-serine acetyltransferaseFAT40_14520Not AvailableNegative2959344 - 295992222148.5
glucan biosynthesis proteinFAT40_14525Not AvailableNegative2959976 - 296163162761.2
nad(p)-dependent alcohol dehydrogenaseFAT40_14530Not AvailablePositive2962069 - 296315737724.9
carboxylesterase/lipase family proteinFAT40_14535Not AvailableNegative2963204 - 296470955047.0
voc family proteinFAT40_14540Not AvailableNegative2964751 - 296609450718.3
protocatechuate 3,4-dioxygenase subunit betaFAT40_14545Not AvailablePositive2966334 - 296707427897.2
protocatechuate 3,4-dioxygenase subunit alphaFAT40_14550Not AvailablePositive2967071 - 296769123121.3

Displaying genes 2901 – 2910 of 5489 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total