Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in environments with or without oxygen. This strain is a chemoheterotroph, obtaining energy through the consumption of organic compounds. Its optimal growth temperature is 37°C, classifying it as mesophilic, which aligns with the typical human body temperature, suggesting a close association with human hosts. The bacterial cells are organized in chains, pairs, and singles, contributing to its diverse morphological arrangements. SIKP114 possesses flagella, indicating mobility, which may play a role in its ability to colonize different environments or hosts. Notably, this strain does not form spores, which is characteristic of its genus. Klebsiella pneumoniae subsp. pneumoniae is known to be free-living but is also associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP) in humans. The presence of one replicon and two membranes further highlights its complexity as a bacterium. The ecological insight gained from understanding strain SIKP114 suggests that its adaptability to different oxygen levels and temperature ranges may contribute to its success as a pathogen in human populations. Its mobility and ability to thrive in host-associated environments underscore its role in infectious disease dynamics, particularly in respiratory infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP114

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP114
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gene Summary

Adenine Count

1197434 bp

Thymine Count

1202004 bp

Guanine Count

1597930 bp

Cytosine Count

1605655 bp

Genome Length

5603023 bp

Protein-coding Genes

5220 genes

Non-Coding Genes

269 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamate-1-semialdehyde 2,1-aminomutaseFAT40_09785Not AvailablePositive1970311 - 197159145330.6
fe(3+)-hydroxamate abc transporter permease fhubFAT40_09790Not AvailableNegative1971728 - 197371070223.0
fe(3+)-hydroxamate abc transporter substrate-binding protein fhudFAT40_09795Not AvailableNegative1973707 - 197459733001.3
fe3+-hydroxamate abc transporter atp-binding protein fhucFAT40_09800Not AvailableNegative1974597 - 197539428729.0
ferrichrome porin fhuaFAT40_09805Not AvailableNegative1975440 - 197764781385.3
bifunctional glycosyl transferase/transpeptidaseFAT40_09810Not AvailableNegative1977882 - 198044095245.0
lipoprotein, puls/outs familyFAT40_09815Not AvailablePositive1981025 - 198140213676.4
general secretion pathway protein gspbFAT40_09820Not AvailableNegative1981441 - 198199819919.7
pullulanase-type alpha-1,6-glucosidaseFAT40_09825Not AvailableNegative1982255 - 1985563119151.0
type ii secretion system protein gspcFAT40_09830Not AvailablePositive1985870 - 198671230245.9

Displaying genes 2011 – 2020 of 5489 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total