Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in environments with or without oxygen. This strain is a chemoheterotroph, obtaining energy through the consumption of organic compounds. Its optimal growth temperature is 37°C, classifying it as mesophilic, which aligns with the typical human body temperature, suggesting a close association with human hosts. The bacterial cells are organized in chains, pairs, and singles, contributing to its diverse morphological arrangements. SIKP114 possesses flagella, indicating mobility, which may play a role in its ability to colonize different environments or hosts. Notably, this strain does not form spores, which is characteristic of its genus. Klebsiella pneumoniae subsp. pneumoniae is known to be free-living but is also associated with significant health effects, particularly in causing pneumonia and community-acquired pneumonia (CAP) in humans. The presence of one replicon and two membranes further highlights its complexity as a bacterium. The ecological insight gained from understanding strain SIKP114 suggests that its adaptability to different oxygen levels and temperature ranges may contribute to its success as a pathogen in human populations. Its mobility and ability to thrive in host-associated environments underscore its role in infectious disease dynamics, particularly in respiratory infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP114

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP114
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP114

Gene Summary

Adenine Count

1197434 bp

Thymine Count

1202004 bp

Guanine Count

1597930 bp

Cytosine Count

1605655 bp

Genome Length

5603023 bp

Protein-coding Genes

5220 genes

Non-Coding Genes

269 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tol-pal system-associated acyl-coa thioesteraseFAT40_08515Not AvailableNegative1702678 - 170308215541.9
cyd operon protein ybgeFAT40_08520Not AvailableNegative1703232 - 170352210906.8
cytochrome bd-i oxidase subunit cydxFAT40_08525Not AvailableNegative1703522 - 17036384196.2
cytochrome d ubiquinol oxidase subunit iiFAT40_08530Not AvailableNegative1703654 - 170479342398.5
cytochrome ubiquinol oxidase subunit iFAT40_08535Not AvailableNegative1704809 - 170637758054.2
succinate--coa ligase subunit alphaFAT40_08545Not AvailableNegative1707203 - 170807229810.3
adp-forming succinate--coa ligase subunit betaFAT40_08550Not AvailableNegative1708072 - 170923841505.2
hypothetical proteinFAT40_08555Not AvailablePositive1709214 - 17094418107.81
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferaseFAT40_08560Not AvailableNegative1709342 - 171056844217.3
2-oxoglutarate dehydrogenase e1 componentFAT40_08565Not AvailableNegative1710583 - 1713390105151.0

Displaying genes 1761 – 1770 of 5489 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total