Klebsiella pneumoniae subsp. pneumoniae strain SIKP112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, able to thrive in both aerobic and anaerobic environments. This strain is characterized as a chemoheterotroph, indicating it derives energy from organic compounds. SIKP112 typically exists in various cell arrangements, appearing as singles, pairs, or chains, and possesses flagella, which contribute to its mobility. The optimal growth temperature for SIKP112 is 37°C, placing it within the mesophilic temperature range, which is conducive to its survival in host-associated environments. This strain is nonsporulating, indicating that it does not form spores as a means of survival under adverse conditions. Ecologically, Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is categorized as free-living, yet it has significant health implications, particularly as a causative agent of pneumonia, including community-acquired pneumonia (CAP). Understanding the traits of this strain can provide insights into its adaptability and pathogenic potential in various environments, emphasizing the importance of monitoring such bacteria in clinical and environmental contexts. The presence of a single replicon and double membranes further supports its classification within the Enterobacteriaceae family, which often displays similar structural and biological characteristics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112

Gene Summary

Adenine Count

1205651 bp

Thymine Count

1193686 bp

Guanine Count

1596744 bp

Cytosine Count

1606742 bp

Genome Length

5602823 bp

Protein-coding Genes

5225 genes

Non-Coding Genes

283 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lysr family transcriptional regulatorFAT59_20250Not AvailableNegative4112108 - 411301633516.8
flavodoxin family proteinFAT59_20255Not AvailablePositive4113103 - 411388529360.9
abc transporter permeaseFAT59_20260Not AvailableNegative4113922 - 411487833714.9
abc transporter permeaseFAT59_20265Not AvailableNegative4114875 - 411584634998.0
sugar abc transporter atp-binding proteinFAT59_20270Not AvailableNegative4115839 - 411732354012.6
autoinducer 2 abc transporter substrate-binding proteinFAT59_20275Not AvailableNegative4117374 - 411836035768.2
tryptophan--trna ligaseFAT59_20280Not AvailablePositive4118862 - 411986937024.7
hlyd family efflux transporter periplasmic adaptor subunitFAT59_20285Not AvailablePositive4120176 - 412124338673.6
abc transporter atp-binding protein/permeaseFAT59_20290Not AvailablePositive4121240 - 4123984100788.0
abc-2 transporter permeaseFAT59_20295Not AvailablePositive4123984 - 412510841113.4

Displaying genes 4121 – 4130 of 5508 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total