Klebsiella pneumoniae subsp. pneumoniae strain SIKP112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, able to thrive in both aerobic and anaerobic environments. This strain is characterized as a chemoheterotroph, indicating it derives energy from organic compounds. SIKP112 typically exists in various cell arrangements, appearing as singles, pairs, or chains, and possesses flagella, which contribute to its mobility. The optimal growth temperature for SIKP112 is 37°C, placing it within the mesophilic temperature range, which is conducive to its survival in host-associated environments. This strain is nonsporulating, indicating that it does not form spores as a means of survival under adverse conditions. Ecologically, Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is categorized as free-living, yet it has significant health implications, particularly as a causative agent of pneumonia, including community-acquired pneumonia (CAP). Understanding the traits of this strain can provide insights into its adaptability and pathogenic potential in various environments, emphasizing the importance of monitoring such bacteria in clinical and environmental contexts. The presence of a single replicon and double membranes further supports its classification within the Enterobacteriaceae family, which often displays similar structural and biological characteristics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112

Gene Summary

Adenine Count

1205651 bp

Thymine Count

1193686 bp

Guanine Count

1596744 bp

Cytosine Count

1606742 bp

Genome Length

5602823 bp

Protein-coding Genes

5225 genes

Non-Coding Genes

283 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nitrate reductase subunit alphaFAT59_11660Not AvailableNegative2395644 - 2399384139846.0
nark family nitrate/nitrite mfs transporterFAT59_11665Not AvailableNegative2399499 - 240088149570.6
tetr family transcriptional regulatorFAT59_11670Not AvailableNegative2401056 - 240163121572.2
efflux mfs transporter kmraFAT59_11675Not AvailablePositive2401755 - 240325451651.3
iclr family transcriptional regulatorFAT59_11680Not AvailableNegative2403249 - 240404628322.6
muconate cycloisomeraseFAT59_11685Not AvailablePositive2404300 - 240541838946.9
muconolactone delta-isomeraseFAT59_11690Not AvailablePositive2405438 - 240572811212.5
catechol 1,2-dioxygenaseFAT59_11695Not AvailablePositive2405795 - 240672134290.3
benzoate 1,2-dioxygenase large subunitFAT59_11700Not AvailablePositive2406831 - 240821352476.7
benzoate 1,2-dioxygenase small subunitFAT59_11705Not AvailablePositive2408213 - 240869819328.6

Displaying genes 2441 – 2450 of 5508 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total