Klebsiella pneumoniae subsp. pneumoniae strain SIKP112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, able to thrive in both aerobic and anaerobic environments. This strain is characterized as a chemoheterotroph, indicating it derives energy from organic compounds. SIKP112 typically exists in various cell arrangements, appearing as singles, pairs, or chains, and possesses flagella, which contribute to its mobility. The optimal growth temperature for SIKP112 is 37°C, placing it within the mesophilic temperature range, which is conducive to its survival in host-associated environments. This strain is nonsporulating, indicating that it does not form spores as a means of survival under adverse conditions. Ecologically, Klebsiella pneumoniae subsp. pneumoniae strain SIKP112 is categorized as free-living, yet it has significant health implications, particularly as a causative agent of pneumonia, including community-acquired pneumonia (CAP). Understanding the traits of this strain can provide insights into its adaptability and pathogenic potential in various environments, emphasizing the importance of monitoring such bacteria in clinical and environmental contexts. The presence of a single replicon and double membranes further supports its classification within the Enterobacteriaceae family, which often displays similar structural and biological characteristics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP112


Gene Summary

Adenine Count

1205651 bp

Thymine Count

1193686 bp

Guanine Count

1596744 bp

Cytosine Count

1606742 bp

Genome Length

5602823 bp

Protein-coding Genes

5225 genes

Non-Coding Genes

283 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamine-hydrolyzing carbamoyl-phosphate synthase small subunitFAT59_05970Not AvailableNegative1210463 - 121161141204.0
4-hydroxy-tetrahydrodipicolinate reductaseFAT59_05975Not AvailableNegative1212069 - 121289028707.4
triphosphoribosyl-dephospho-coa synthase citgFAT59_05980Not AvailableNegative1213119 - 121402732733.6
citrate lyase subunit alphaFAT59_05985Not AvailableNegative1214046 - 121557254661.5
citrate (pro-3s)-lyase subunit betaFAT59_05990Not AvailableNegative1215583 - 121645231353.7
citrate lyase acyl carrier proteinFAT59_05995Not AvailableNegative1216449 - 121674210400.7
[citrate (pro-3s)-lyase] ligaseFAT59_06000Not AvailableNegative1216773 - 121780138478.8
citrate/sodium symporter citnFAT59_06005Not AvailablePositive1218058 - 121939847474.7
oxaloacetate decarboxylase gamma chainFAT59_06010Not AvailablePositive1219554 - 12196302850.69
mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomeraseFAT59_06015Not AvailableNegative1219631 - 122098850777.4

Displaying genes 1361 – 1370 of 5508 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total