Klebsiella pneumoniae subsp. pneumoniae strain SIKP111

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP111 is a Gram-negative, rod-shaped bacterium that exhibits a range of notable traits. It is categorized as a chemoheterotroph, indicating that it derives its energy from organic compounds. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP111 typically exists in various arrangements, including singles, pairs, and chains, which may influence its pathogenicity and interaction with host organisms. This strain is associated with human hosts and is known to cause pneumonia, specifically community-acquired pneumonia (CAP). Its optimal growth temperature is 37°C, which aligns with the human body temperature, suggesting its adaptation to the human host environment. The bacterium possesses flagella, enabling mobility, and has a mesophilic temperature range, further supporting its survival in human-associated habitats. Klebsiella pneumoniae subsp. pneumoniae strain SIKP111 is nonsporulating and has a unique biotic relationship as a free-living organism, which may play a role in its ecological niche. The bacterium contains a single replicon and has a double-membrane structure, characteristic of Gram-negative bacteria. Understanding the traits of SIKP111 provides insight into its pathogenic potential and ecological role. Its ability to thrive in host-associated environments and its mobility may contribute to its transmission and virulence in community settings, emphasizing the importance of monitoring such strains in public health contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP111

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP111
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP111

Gene Summary

Adenine Count

1199026 bp

Thymine Count

1200950 bp

Guanine Count

1606233 bp

Cytosine Count

1598393 bp

Genome Length

5604602 bp

Protein-coding Genes

5216 genes

Non-Coding Genes

272 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
autoinducer 2 abc transporter permease lsrcFAT52_16110Not AvailablePositive3279535 - 328056936056.2
autoinducer 2 import system permease lsrdFAT52_16115Not AvailablePositive3280570 - 328156834850.9
autoinducer 2 abc transporter substrate-binding protein lsrbFAT52_16120Not AvailablePositive3281570 - 328257135930.1
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolaseFAT52_16125Not AvailablePositive3282583 - 328347032413.0
(4s)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomeraseFAT52_16130Not AvailablePositive3283467 - 328376311517.9
putrescine aminotransferaseFAT52_16135Not AvailableNegative3283810 - 328518949506.0
padr family transcriptional regulatorFAT52_16140Not AvailableNegative3285447 - 328600120785.8
siderophore-interacting proteinFAT52_16145Not AvailablePositive3286242 - 328701528942.2
glycerone kinaseFAT52_16150Not AvailableNegative3287171 - 328882057383.7
dihydroxyacetone kinase subunit dhamFAT52_16155Not AvailableNegative3288896 - 329031750367.2

Displaying genes 3291 – 3300 of 5488 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total