Klebsiella pneumoniae subsp. pneumoniae strain SIKP111

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP111 is a Gram-negative, rod-shaped bacterium that exhibits a range of notable traits. It is categorized as a chemoheterotroph, indicating that it derives its energy from organic compounds. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. SIKP111 typically exists in various arrangements, including singles, pairs, and chains, which may influence its pathogenicity and interaction with host organisms. This strain is associated with human hosts and is known to cause pneumonia, specifically community-acquired pneumonia (CAP). Its optimal growth temperature is 37°C, which aligns with the human body temperature, suggesting its adaptation to the human host environment. The bacterium possesses flagella, enabling mobility, and has a mesophilic temperature range, further supporting its survival in human-associated habitats. Klebsiella pneumoniae subsp. pneumoniae strain SIKP111 is nonsporulating and has a unique biotic relationship as a free-living organism, which may play a role in its ecological niche. The bacterium contains a single replicon and has a double-membrane structure, characteristic of Gram-negative bacteria. Understanding the traits of SIKP111 provides insight into its pathogenic potential and ecological role. Its ability to thrive in host-associated environments and its mobility may contribute to its transmission and virulence in community settings, emphasizing the importance of monitoring such strains in public health contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP111

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP111
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP111

Gene Summary

Adenine Count

1199026 bp

Thymine Count

1200950 bp

Guanine Count

1606233 bp

Cytosine Count

1598393 bp

Genome Length

5604602 bp

Protein-coding Genes

5216 genes

Non-Coding Genes

272 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
zinc-binding alcohol dehydrogenase family proteinFAT52_06090Not AvailableNegative1280819 - 128176632553.1
marr family transcriptional regulatorFAT52_06095Not AvailablePositive1281841 - 128232317768.4
tryptophan synthase subunit alphaFAT52_06100Not AvailableNegative1282327 - 128313628545.3
tryptophan synthase subunit betaFAT52_06105Not AvailableNegative1283136 - 128432942965.7
bifunctional indole-3-glycerol-phosphate synthase trpc/phosphoribosylanthranilate isomerase trpfFAT52_06110Not AvailableNegative1284339 - 128569749330.9
bifunctional anthranilate synthase glutamate amidotransferase component trpg/anthranilate phosphoribosyltransferase trpdFAT52_06115Not AvailableNegative1285701 - 128729656625.1
anthranilate synthase component 1FAT52_06120Not AvailableNegative1287296 - 128885857441.7
5'-3' exoribonucleaseFAT52_06125Not AvailablePositive1289147 - 129001031603.8
threonylcarbamoyl-amp synthaseFAT52_06130Not AvailablePositive1290027 - 129064723110.1
eama/rhat family transporterFAT52_06135Not AvailableNegative1290669 - 129157732016.2

Displaying genes 1411 – 1420 of 5488 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total