Klebsiella pneumoniae subsp. pneumoniae strain SIKP110

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP110 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of thriving in a host-associated habitat, suggesting its adaptability to various environments, including human hosts. SIKP110 can be found in different arrangements, including chains, pairs, and singles, and possesses flagella, indicating its mobility. The strain operates optimally at a temperature of 37°C, which aligns with its mesophilic nature, making it well-suited for survival in warm-blooded hosts. SIKP110 has a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Importantly, this strain is nonsporulating, which influences its survival strategies under varying environmental conditions. Klebsiella pneumoniae subsp. pneumoniae is known for its clinical significance, particularly in causing pneumonia, including community-acquired pneumonia (CAP). The presence of this bacterium in the environment, along with its free-living biotic relationships, highlights its potential role in the microbial ecology of both pathogenic and non-pathogenic contexts. The understanding of SIKP110's traits is crucial for developing strategies to manage infections it may cause, particularly in vulnerable populations. The combination of its mobility, optimal growth temperature, and pathogenicity underscores the importance of monitoring this strain in public health contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP110

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP110
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP110

Gene Summary

Adenine Count

1158892 bp

Thymine Count

1153863 bp

Guanine Count

1552018 bp

Cytosine Count

1559996 bp

Genome Length

5424769 bp

Protein-coding Genes

4978 genes

Non-Coding Genes

233 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenylosuccinate lyaseFAS48_19750Not AvailableNegative4032780 - 403415051646.8
high frequency lysogenization protein hfldFAS48_19755Not AvailableNegative4034154 - 403479522937.0
trna 2-thiouridine(34) synthase mnmaFAS48_19760Not AvailableNegative4034850 - 403595641018.8
nudix hydrolaseFAS48_19765Not AvailableNegative4036013 - 403647117302.6
23s rrna pseudouridine(2457) synthase rlueFAS48_19770Not AvailableNegative4036488 - 403713824699.8
nadp-dependent isocitrate dehydrogenaseFAS48_19775Not AvailablePositive4037379 - 403862945751.3
winged helix-turn-helix transcriptional regulatorFAS48_19780Not AvailableNegative4038902 - 403961525923.4
amino acid-binding proteinFAS48_19785Not AvailableNegative4039612 - 404000413933.6
antibiotic biosynthesis monooxygenaseFAS48_19790Not AvailableNegative4039997 - 404032012077.2
hypothetical proteinFAS48_19795Not AvailablePositive4040564 - 40407496708.97

Displaying genes 3901 – 3910 of 5211 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total