Klebsiella pneumoniae strain SIKP152 161_NODE_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP152 161_NODE_74 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This organism typically exists in chains, pairs, or as single cells, and is motile due to the presence of flagella. With an optimal growth temperature of 37°C, it thrives in mesophilic conditions. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and several other animals and plants, indicating a diverse ecological niche. Notably, it has been identified as a significant pathogen in humans, associated with a range of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others, highlighting its clinical relevance and potential to cause severe infections such as sepsis and meningitis. Klebsiella pneumoniae SIKP152 161_NODE_74 is nonsporulating and possesses a single replicon and two membranes, typical of its classification within the Enterobacteriaceae family. Its ability to cause infections across multiple hosts reflects its adaptability and pathogenic potential. This bacterium's free-living biotic relationship suggests a versatile lifestyle, allowing it to thrive in diverse environments, which may contribute to its prevalence in clinical settings and its role as a significant opportunistic pathogen. Understanding its ecological interactions and pathogenic mechanisms is critical for developing strategies to manage infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP152 161_NODE_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP152 161_NODE_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP152 161_NODE_74, whole genome

Gene Summary

Adenine Count

1188353 bp

Thymine Count

1185614 bp

Guanine Count

1577486 bp

Cytosine Count

1590568 bp

Genome Length

5542021 bp

Protein-coding Genes

5035 genes

Non-Coding Genes

441 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer protein trarFAS57_26900Not AvailableNegative5358447 - 53586688299.92
type iv conjugative transfer system protein travFAS57_26905Not AvailableNegative5358803 - 535931818428.2
conjugal transfer protein trbgFAS57_26910Not AvailableNegative5359315 - 53595669126.86
conjugal transfer protein trbdFAS57_26915Not AvailableNegative5359559 - 53597205637.0
duf2689 domain-containing proteinFAS57_26920Not AvailableNegative5359742 - 53598794828.92
trap family proteinFAS57_26925Not AvailableNegative5359866 - 536045021159.3
type iv conjugative transfer system protein traeFAS57_26930Not AvailableNegative5360437 - 536100321197.5
type iv conjugative transfer system protein tralFAS57_26935Not AvailableNegative5361025 - 536133611904.7
pilinFAS57_26940Not AvailableNegative5361351 - 536171612798.3
conjugal transfer relaxosome protein trayFAS57_26945Not AvailableNegative5361759 - 53619748117.65

Displaying genes 5281 – 5290 of 5476 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total