Klebsiella pneumoniae strain SIKP152 161_NODE_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP152 161_NODE_74 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This organism typically exists in chains, pairs, or as single cells, and is motile due to the presence of flagella. With an optimal growth temperature of 37°C, it thrives in mesophilic conditions. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and several other animals and plants, indicating a diverse ecological niche. Notably, it has been identified as a significant pathogen in humans, associated with a range of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others, highlighting its clinical relevance and potential to cause severe infections such as sepsis and meningitis. Klebsiella pneumoniae SIKP152 161_NODE_74 is nonsporulating and possesses a single replicon and two membranes, typical of its classification within the Enterobacteriaceae family. Its ability to cause infections across multiple hosts reflects its adaptability and pathogenic potential. This bacterium's free-living biotic relationship suggests a versatile lifestyle, allowing it to thrive in diverse environments, which may contribute to its prevalence in clinical settings and its role as a significant opportunistic pathogen. Understanding its ecological interactions and pathogenic mechanisms is critical for developing strategies to manage infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP152 161_NODE_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP152 161_NODE_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP152 161_NODE_74, whole genome

Gene Summary

Adenine Count

1188353 bp

Thymine Count

1185614 bp

Guanine Count

1577486 bp

Cytosine Count

1590568 bp

Genome Length

5542021 bp

Protein-coding Genes

5035 genes

Non-Coding Genes

441 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sulfurtransferase tuseFAS57_20450Not AvailablePositive4172647 - 417297612423.0
acylphosphataseFAS57_20455Not AvailableNegative4172973 - 417325410248.2
helix-turn-helix domain-containing proteinFAS57_20460Not AvailableNegative4173303 - 417409129533.1
ybhb/ybcl family raf kinase inhibitor-like proteinFAS57_20465Not AvailableNegative4174109 - 417466318872.3
23s rrna (cytosine(1962)-c(5))-methyltransferase rlmiFAS57_20470Not AvailablePositive4174854 - 417605644661.7
heat shock protein hspqFAS57_20475Not AvailablePositive4176116 - 417643311881.8
coa-binding proteinFAS57_20480Not AvailableNegative4176464 - 417687714717.0
methylglyoxal synthaseFAS57_20485Not AvailablePositive4177032 - 417749016755.5
dna helicase ivFAS57_20490Not AvailableNegative4177502 - 417955677551.1
yccf domain-containing proteinFAS57_20495Not AvailablePositive4179681 - 418012716477.6

Displaying genes 4331 – 4340 of 5476 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total