Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in a variety of oxygen conditions. This strain is categorized as a chemoheterotroph, utilizing organic compounds as its energy source. SIKP150 typically exists in chains, pairs, or as single cells, demonstrating versatility in its cellular arrangement. In terms of mobility, this strain is motile, possessing flagella, which aids in its movement within its host-associated habitat. It has an optimal growth temperature of 37°C, fitting within the mesophilic range, which is conducive to its role as a pathogen in humans. Klebsiella pneumoniae subsp. pneumoniae is notably implicated in causing pneumonia, particularly community-acquired pneumonia (CAP), which poses significant health risks. This bacterium features a unique cellular structure comprising two membranes and contains a single replicon, which is typical for many members of the Enterobacteriaceae family. Importantly, SIKP150 does not undergo sporulation, indicating a reliance on favorable environmental conditions for survival and replication. The presence of Klebsiella pneumoniae subsp. pneumoniae in human-associated environments highlights its ecological role as a free-living organism that can transition to pathogenicity. Its ability to adapt to various environments underscores the importance of understanding its behavior in clinical settings, as it can lead to serious health implications, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP150

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP150
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gene Summary

Adenine Count

1188960 bp

Thymine Count

1184674 bp

Guanine Count

1572499 bp

Cytosine Count

1601636 bp

Genome Length

5547769 bp

Protein-coding Genes

5389 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tryptophan--trna ligaseFAS46_21245Not AvailableNegative4328802 - 432980937006.7
autoinducer 2 abc transporter substrate-binding proteinFAS46_21250Not AvailablePositive4330310 - 433129635768.2
sugar abc transporter atp-binding proteinFAS46_21255Not AvailablePositive4331347 - 433283154062.7
abc transporter permeaseFAS46_21260Not AvailablePositive4332824 - 433379534998.0
abc transporter permeaseFAS46_21265Not AvailablePositive4333792 - 433474833708.9
nad(p)h-dependent oxidoreductaseFAS46_21270Not AvailableNegative4334785 - 433556729373.9
lysr family transcriptional regulatorFAS46_21275Not AvailablePositive4335654 - 433656233441.7
fosa family fosfomycin resistance glutathione transferaseFAS46_21280Not AvailablePositive4336556 - 433697815679.5
hypothetical proteinFAS46_21285Not AvailableNegative4337042 - 43372457407.37
type i restriction endonuclease subunit rFAS46_21290Not AvailableNegative4337258 - 4340521124880.0

Displaying genes 4181 – 4190 of 5476 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total