Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in a variety of oxygen conditions. This strain is categorized as a chemoheterotroph, utilizing organic compounds as its energy source. SIKP150 typically exists in chains, pairs, or as single cells, demonstrating versatility in its cellular arrangement. In terms of mobility, this strain is motile, possessing flagella, which aids in its movement within its host-associated habitat. It has an optimal growth temperature of 37°C, fitting within the mesophilic range, which is conducive to its role as a pathogen in humans. Klebsiella pneumoniae subsp. pneumoniae is notably implicated in causing pneumonia, particularly community-acquired pneumonia (CAP), which poses significant health risks. This bacterium features a unique cellular structure comprising two membranes and contains a single replicon, which is typical for many members of the Enterobacteriaceae family. Importantly, SIKP150 does not undergo sporulation, indicating a reliance on favorable environmental conditions for survival and replication. The presence of Klebsiella pneumoniae subsp. pneumoniae in human-associated environments highlights its ecological role as a free-living organism that can transition to pathogenicity. Its ability to adapt to various environments underscores the importance of understanding its behavior in clinical settings, as it can lead to serious health implications, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP150

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP150
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gene Summary

Adenine Count

1188960 bp

Thymine Count

1184674 bp

Guanine Count

1572499 bp

Cytosine Count

1601636 bp

Genome Length

5547769 bp

Protein-coding Genes

5389 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
5'-3' exoribonucleaseFAS46_21140Not AvailableNegative4306038 - 430690131603.8
anthranilate synthase component 1FAS46_21145Not AvailablePositive4307190 - 430875257411.7
bifunctional anthranilate synthase glutamate amidotransferase component trpg/anthranilate phosphoribosyltransferase trpdFAS46_21150Not AvailablePositive4308752 - 431034756625.1
bifunctional indole-3-glycerol-phosphate synthase trpc/phosphoribosylanthranilate isomerase trpfFAS46_21155Not AvailablePositive4310351 - 431170949299.8
tryptophan synthase subunit betaFAS46_21160Not AvailablePositive4311719 - 431291242952.6
tryptophan synthase subunit alphaFAS46_21165Not AvailablePositive4312912 - 431372128545.3
marr family transcriptional regulatorFAS46_21170Not AvailableNegative4313725 - 431420717768.4
zinc-binding alcohol dehydrogenase family proteinFAS46_21175Not AvailablePositive4314282 - 431522932525.1
sdr family nad(p)-dependent oxidoreductaseFAS46_21185Not AvailablePositive4315656 - 431636325714.1
catecholate siderophore receptor fiuFAS46_21190Not AvailablePositive4316673 - 431895881623.2

Displaying genes 4161 – 4170 of 5476 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total