Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in a variety of oxygen conditions. This strain is categorized as a chemoheterotroph, utilizing organic compounds as its energy source. SIKP150 typically exists in chains, pairs, or as single cells, demonstrating versatility in its cellular arrangement. In terms of mobility, this strain is motile, possessing flagella, which aids in its movement within its host-associated habitat. It has an optimal growth temperature of 37°C, fitting within the mesophilic range, which is conducive to its role as a pathogen in humans. Klebsiella pneumoniae subsp. pneumoniae is notably implicated in causing pneumonia, particularly community-acquired pneumonia (CAP), which poses significant health risks. This bacterium features a unique cellular structure comprising two membranes and contains a single replicon, which is typical for many members of the Enterobacteriaceae family. Importantly, SIKP150 does not undergo sporulation, indicating a reliance on favorable environmental conditions for survival and replication. The presence of Klebsiella pneumoniae subsp. pneumoniae in human-associated environments highlights its ecological role as a free-living organism that can transition to pathogenicity. Its ability to adapt to various environments underscores the importance of understanding its behavior in clinical settings, as it can lead to serious health implications, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain SIKP150

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain SIKP150
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain SIKP150

Gene Summary

Adenine Count

1188960 bp

Thymine Count

1184674 bp

Guanine Count

1572499 bp

Cytosine Count

1601636 bp

Genome Length

5547769 bp

Protein-coding Genes

5389 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutaredoxin 3FAS46_11165Not AvailableNegative2290429 - 22906809149.05
rhodanese-like domain-containing proteinFAS46_11170Not AvailableNegative2290785 - 229121615587.2
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseFAS46_11175Not AvailablePositive2291462 - 229300656024.1
murein hydrolase activator envcFAS46_11180Not AvailablePositive2293016 - 229428746932.7
divergent polysaccharide deacetylase family proteinFAS46_11185Not AvailablePositive2294291 - 229523834882.1
glycosyltransferase family 2 proteinFAS46_11190Not AvailableNegative2295244 - 229603229762.7
l-threonine 3-dehydrogenaseFAS46_11195Not AvailableNegative2296201 - 229722637257.2
glycine c-acetyltransferaseFAS46_11200Not AvailableNegative2297239 - 229843243158.7
adp-glyceromanno-heptose 6-epimeraseFAS46_11205Not AvailablePositive2298646 - 229957834941.0
adp-heptose--lps heptosyltransferase rfafFAS46_11210Not AvailablePositive2299588 - 230064639291.6

Displaying genes 2211 – 2220 of 5476 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total