Klebsiella pneumoniae strain SIKP134 143_NODE_78

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain SIKP134 (accession STCC00000000.1) is a Gram-negative, rod-shaped bacterium characterized by its mobility and the presence of flagella. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, and it is classified as a chemoheterotroph, relying on organic compounds for energy. The bacterium typically inhabits host-associated environments, suggesting a close relationship with various organisms. Its preferred habitat includes a diverse range of hosts such as Homo sapiens (humans), Gallus gallus (chickens), and other Metazoa, including fish and mammals. This wide host range highlights the strain’s adaptability and potential for cross-species transmission. In terms of pathogenicity, Klebsiella pneumoniae strain SIKP134 is known to cause a variety of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause multiple infections signifies its clinical importance and underscores the need for effective monitoring and treatment strategies. The strain's optimal growth temperature is 37°C, which is consistent with its association with warm-blooded hosts. Additionally, it has a mesophilic temperature range, further supporting its role in human and animal infections. In summary, Klebsiella pneumoniae strain SIKP134 is a nonsporulating, opportunistic pathogen with significant implications for human health. Its diverse host interactions and pathogenic capabilities suggest a complex ecological role in both health and disease, emphasizing the need for further research into its transmission dynamics and resistance mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain SIKP134 143_NODE_78

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain SIKP134 143_NODE_78
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain SIKP134 143_NODE_78, whole genome

Gene Summary

Adenine Count

1193241 bp

Thymine Count

1190923 bp

Guanine Count

1596489 bp

Cytosine Count

1588056 bp

Genome Length

5568709 bp

Protein-coding Genes

5146 genes

Non-Coding Genes

367 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinFAS26_08290Not AvailablePositive1693415 - 169434434046.4
AttlNot AvailableNot AvailablePositive1694433 - 1694456Not Available
Hypothetical proteinFAS26_08295Not AvailableNegative1694551 - 169492213211.5
Hypothetical proteinFAS26_08300Not AvailableNegative1694879 - 16951189221.6
imma/irre family metallo-endopeptidaseFAS26_08305Not AvailableNegative1695669 - 169612116770.2
Putative transcriptional regulatorFAS26_08310Not AvailableNegative1696211 - 169657013196.8
hypotheticalFAS26_08315Not AvailableNegative1697123 - 16972062996.66
Hypothetical proteinFAS26_08320Not AvailableNegative1697222 - 169764416008.3
Dna invertase-like proteinFAS26_08325Not AvailableNegative1697722 - 16979046948.51
hypothetical proteinFAS26_08330Not AvailableNegative1697916 - 169871627719.4

Displaying genes 1 – 10 of 5513 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total